DB identifier
|
AT4G20260 | Secondary Identifier
|
locus:2120402 |
| Name
|
plasma-membrane associated cation-binding protein 1 | Brief Description | plasma-membrane associated cation-binding protein 1 |
| TAIR Computational Description | plasma-membrane associated cation-binding protein 1;(source:Araport11) |
| TAIR Curator Summary | Encodes a Ca2+ and Cu2+ binding protein. N-terminal myristylation on glycine 2 appears to enable it to associate tightly with the plasma membrane. Recombinant PCaP1 interacts strongly with phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) and PtdIns (3,4,5)P3, and weakly with PtdIns(3,5)P2 and PtdIns(4,5). It also interacts with calmodulin (CaM) in a calcium-dependent manner. CaM does not interfere with PCaP1 membrane localization but does weaken interactions between it and the PtdInsPs. PCaP1 has an apparent Kd of 10 uM for Cu2+ and can bind six ions per protein. Transcript levels for PCaP1 first fall and then rise following exposure to CuCl2. Mannitol, sorbitol, and the flg22 oligopeptide also increase expression levels. The mRNA is cell-to-cell mobile. |
| TAIR Short Description | plasma-membrane associated cation-binding protein 1 |
| TAIR Aliases | ATPCAP1, MDP25, PCAP1 |
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