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Gene : VRN2 A. thaliana

DB identifier  ? AT4G16845 Secondary Identifier  ? locus:3685330
Name  ? REDUCED VERNALIZATION RESPONSE 2 Brief Description  VEFS-Box of polycomb protein
TAIR Computational Description  VEFS-Box of polycomb protein;(source:Araport11)
TAIR Curator Summary  The VERNALIZATION2 (VRN2) gene mediates vernalization and encodes a nuclear-localized zinc finger protein with similarity to Polycomb group (PcG) proteins of plants and animals. In wild-type Arabidopsis, vernalization results in the stable reduction of the levels of the floral repressor FLC. In vrn2 mutants, FLC expression is downregulated normally in response to vernalization, but instead of remaining low, FLC mRNA levels increase when plants are returned to normal temperatures. VRN2 maintains FLC repression after a cold treatment, serving as a mechanism for the cellular memory of vernalization. Required for complete repression of FLC. Required for the methylation of histone H3
TAIR Short Description  VEFS-Box of polycomb protein
TAIR Aliases  VRN2

2 Gene Rifs

1 Organism

40 Publications

0 Synonyms

Genomics

Genome feature

Region: gene ? Length: 3810  
Location: Chr4:9476069-9479878

Gene models - VRN2 AT4G16845

? Gene models

Transcripts: 2  Exons: 29  Introns: 27 

Overlapping Features

? Genome features that overlap coordinates of this Gene

20 Child Features

1 Cross References

1 Downstream Intergenic Region

0 Located Features

1 Upstream Intergenic Region

Proteins

Curated comments from UniProt

Type Comment Proteins
VRN2_ARATH-2 VRN2_ARATH function Polycomb group (PcG) protein. Plays a central role in vernalization by maintaining repressed the homeotic gene FLC, a floral repressor, after a cold treatment. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development. PcG proteins are not required to initiate repression, but to maintain it during later stages of development. They probably act via the methylation of histones, rendering chromatin heritably changed in its expressibility. Associates constitutively along the whole FLC locus.
VRN2_ARATH-2 VRN2_ARATH F4JMM5_ARATH similarity Belongs to the VEFS (VRN2-EMF2-FIS2-SU(Z)12) family.
VRN2_ARATH-2 VRN2_ARATH tissue specificity Weakly expressed. Expressed both during, and in the absence of vernalization.

3 Proteins

Function

Gene Ontology

cellular component
nucleus  ? ECO  
chromatin silencing complex  ? ECO  
molecular function
DNA-binding transcription factor activity  ? ECO  
metal ion binding  ? ECO  
biological process
vernalization response  ? ECO  
response to cold  ? ECO  

Interactions

Interaction Network

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Expression

eFP Visualization

Data Source: BAR




Co-expression

Querying ATTED Service...
Data Source: ATTED-II
Top N
LS: LS is a monotonic transformation (negative logit) of MR index. Larger LS indicates stronger co-expression.

 

Homology

Phytozome Homologs

Data Source: Phytozome


0 Homologues

 

Other

9 Data Sets