Proteins
Curated comments from UniProt
Type | Comment | Proteins |
---|---|---|
ATXR3_ARATH | function | Histone methyltransferase specifically required for trimethylation of 'Lys-4' of histone H3 (H3K4me3) and is crucial for both sporophyte and gametophyte development (PubMed:20937886, PubMed:21037105). Function as a diurnal 'writer' to counteract the nocturne 'eraser' demethylase activity of JMJ14 thus orchestrating the circadian rythm of histone modifications (e.g. H3K4me3) and modulating the rythmic expression of diurnal target genes; this mechanism relies also on the circadian clock oscillators CCA1 and LHY (PubMed:31429787). |
ATXR3_ARATH | similarity | Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. TRX/MLL subfamily. |
ATXR3_ARATH | tissue specificity | Expressed in roots, leaves, stems and inflorescences. |
Function
Gene Ontology
cellular component | |
---|---|
nucleus | ECO |
molecular function | |
histone H3K4 methyltransferase activity | ECO |
histone H3K4 trimethyltransferase activity | ECO |
metal ion binding | ECO |
biological process | |
vegetative to reproductive phase transition of meristem | ECO |
post-embryonic development | ECO |
stamen development | ECO |
circadian rhythm | ECO |
epigenetic regulation of gene expression | ECO |
carpel development | ECO |
methylation | ECO |
Interactions
Interaction Network
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