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Gene : AT4G04880 A. thaliana

DB identifier  ? AT4G04880 Secondary Identifier  ? locus:2138967
Brief Description  adenosine/AMP deaminase family protein
TAIR Computational Description  adenosine/AMP deaminase family protein;(source:Araport11)
TAIR Curator Summary  Encodes an N6-mAMP deaminase (ADAL, renamed MAPDA) that catabolizes N6-mAMP derived from turnover of m6A-modified RNA to inosine monophosphate in vivo by hydrolytically removing the aminomethyl group.
TAIR Short Description  adenosine/AMP deaminase family protein
TAIR Aliases  ADAL, MAPDA

1 Gene Rifs

1 Organism

7 Publications

0 Synonyms

Genomics

Genome feature

Region: gene ? Length: 2420  
Location: Chr4:2464840-2467259 reverse strand

Gene models - AT4G04880 AT4G04880

? Gene models

Transcripts: 3  Exons: 31  Introns: 28 

Overlapping Features

? Genome features that overlap coordinates of this Gene

18 Child Features

0 Cross References

1 Downstream Intergenic Region

0 Located Features

1 Upstream Intergenic Region

Proteins

Curated comments from UniProt

Type Comment Proteins
ADAL_ARATH function Catalyzes the hydrolysis of the free cytosolic methylated adenosine nucleotide N(6)-methyl-AMP (N6-mAMP) to produce inositol monophosphate (IMP) and methylamine (PubMed:29884623, PubMed:30721978, PubMed:31318636). Is required for the catabolism of cytosolic N6-mAMP, which is derived from the degradation of mRNA containing N6-methylated adenine (m6A) (PubMed:29884623). Does not possess deaminase activity toward adenosine, AMP, N6-methyladenosine, or N6-mATP in vitro (PubMed:29884623).
ADAL_ARATH similarity Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

3 Proteins

Function

Gene Ontology

cellular component
cytosol  ? ECO  
molecular function
adenosine deaminase activity  ? ECO  
deaminase activity  ? ECO  
metal ion binding  ? ECO  
N6-methyl-AMP deaminase activity  ? ECO  
biological process
nucleotide metabolic process  ? ECO  
inosine biosynthetic process  ? ECO  
RNA catabolic process  ? ECO  
adenosine catabolic process  ? ECO  

Interactions

Interaction Network

Expression

eFP Visualization

Data Source: BAR




Co-expression

Querying ATTED Service...
Data Source: ATTED-II
Top N
LS: LS is a monotonic transformation (negative logit) of MR index. Larger LS indicates stronger co-expression.

 

Homology

Phytozome Homologs

Data Source: Phytozome


0 Homologues

 

Other

7 Data Sets