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Gene : TIR1 A. thaliana

DB identifier  ? AT3G62980 Secondary Identifier  ? locus:2099237
Name  ? TRANSPORT INHIBITOR RESPONSE 1 Brief Description  F-box/RNI-like superfamily protein
TAIR Computational Description  F-box/RNI-like superfamily protein;(source:Araport11)
TAIR Curator Summary  Encodes an auxin receptor that mediates auxin-regulated transcription. It contains leucine-rich repeats and an F-box and interacts with ASK1, ASK2 and AtCUL1 to form SCF-TIR1, an SCF ubiquitin ligase complex. Related to yeast Grr1p and human SKP2 proteins, involved in ubiquitin-mediated processes. Required for normal response to auxin and repressed in response to flagellin. As part of the SCF complex and in the presence of auxin, TIR1 interacts with Aux/IAA transcriptional repressor proteins and mediates their degradation. Mutations in TIR1 block auxin stimulation of flavonoid synthesis.
TAIR Short Description  F-box/RNI-like superfamily protein
TAIR Aliases  AtTIR1, TIR1

31 Gene Rifs

1 Organism

136 Publications

0 Synonyms

Genomics

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4 Child Features

1 Cross References

1 Downstream Intergenic Region

0 Located Features

1 Upstream Intergenic Region

Proteins

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1 Proteins

Function

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Interactions

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Expression

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Homology

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9 Data Sets