Proteins
Curated comments from UniProt
Type | Comment | Proteins |
---|---|---|
PEL2_ARATH | function | Component of the Pelota-HBS1L complex, a complex that recognizes stalled ribosomes and triggers the No-Go Decay (NGD) pathway. In the Pelota-HBS1L complex, pelo recognizes ribosomes stalled at the 3' end of an mRNA and engages stalled ribosomes by destabilizing mRNA in the mRNA channel. Following ribosome-binding, the Pelota-HBS1L complex promotes the disassembly of stalled ribosomes, followed by degradation of damaged mRNAs as part of the NGD pathway. |
PEL2_ARATH | similarity | Belongs to the eukaryotic release factor 1 family. Pelota subfamily. |
Function
Gene Ontology
cellular component | |
---|---|
nucleus | ECO |
cytoplasm | ECO |
molecular function | |
metal ion binding | ECO |
biological process | |
nuclear-transcribed mRNA catabolic process, non-stop decay | ECO |
RNA surveillance | ECO |
nuclear-transcribed mRNA catabolic process, no-go decay | ECO |
Interactions
Interaction Network
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