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Gene : ZAR1 A. thaliana

DB identifier  ? AT3G50950 Secondary Identifier  ? locus:2078012
Name  ? HOPZ-ACTIVATED RESISTANCE 1 Brief Description  HOPZ-ACTIVATED RESISTANCE 1
TAIR Computational Description  HOPZ-ACTIVATED RESISTANCE 1;(source:Araport11)
TAIR Curator Summary  Encodes a canonical CC-type NLR protein that is required for the recognition of the T3SE HopZ1a as well as several other Hop effectors from the pathogenic bacteria P. syringae.
TAIR Short Description  HOPZ-ACTIVATED RESISTANCE 1
TAIR Aliases  ZAR1

11 Gene Rifs

1 Organism

30 Publications

0 Synonyms

Genomics

Genome feature

Region: gene ? Length: 3126  
Location: Chr3:18935674-18938799

Gene models - ZAR1 AT3G50950

? Gene models

Transcripts: 2  Exons: 4  Introns: 2 

Overlapping Features

? Genome features that overlap coordinates of this Gene

6 Child Features

1 Cross References

0 Downstream Intergenic Region

0 Located Features

1 Upstream Intergenic Region

Proteins

Curated comments from UniProt

Type Comment Proteins
R13L4_ARATH function CC-NB-LRR receptor-like protein required for recognition of pathogenic bacteria type III effectors (T3E) such as Pseudomonas syringae HopZ1a and HopF2a and Xanthomonas campestris pv. campestris (Xcc) XopAC/AvrAC; this recognition requires ZED1-related kinases (e.g. PBL2, ZRK3 and ZED1/ZRK5) (PubMed:20368970, PubMed:26355215, PubMed:28288096, PubMed:28652264, PubMed:30948526, PubMed:30948527). Confers allele-specific recognition and virulence attenuation of HopZ1a (PubMed:20368970). Immunity mediated by RPP13L4/ZAR1 is independent of several genes required by other resistance protein signaling pathways such as NDR1 and RAR1 (PubMed:20368970). Together with ZED1/ZRK5, involved in the regulation of the ambient temperature-sensitive intersection of growth and immune response in the absence of pathogens (PubMed:28499073).
R13L4_ARATH similarity Belongs to the disease resistance NB-LRR family. RPP13 subfamily.
R13L4_ARATH subcellular location Associates with the plasma membrane in the presence of the Xanthomonas campestris effector XopAC/AvrAC.

1 Proteins

Function

Gene Ontology

cellular component
plasma membrane  ? ECO  
nucleus  ? ECO  
molecular function
ADP binding  ? ECO  
biological process
defense response to bacterium  ? ECO  
regulation of immune response  ? ECO  
defense response to Gram-negative bacterium  ? ECO  

Interactions

Interaction Network

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Expression

eFP Visualization

Data Source: BAR




Co-expression

Querying ATTED Service...
Data Source: ATTED-II
Top N
LS: LS is a monotonic transformation (negative logit) of MR index. Larger LS indicates stronger co-expression.

 

Homology

Phytozome Homologs

Data Source: Phytozome


0 Homologues

 

Other

9 Data Sets