DB identifier | AT3G50630 | Secondary Identifier | locus:2101679 |
Name | KIP-related protein 2 | Brief Description | KIP-related protein 2 |
TAIR Computational Description | KIP-related protein 2;(source:Araport11) |
TAIR Curator Summary | Kip-related protein (KRP) gene, encodes CDK (cyclin-dependent kinase) inhibitor (CKI), negative regulator of cell division. A member of seven KRP genes found in Arabidopsis thaliana. Differential expression patterns for distinct KRPs were revealed by in situ hybridization. Gene was isolated from a yeast two hybrid screen as an interacting protein of CDC2A. Recombinant protein has a strong kinase inhibitor activity in vitro. Transcript is expressed in all tissues examined but is differentially distributed from ICK1. Controls the onset of the endoreduplication cycle through inhibition of CDKA;1. The KRP2 protein abundance is regulated by proteolysis through CDKB1;1 phosphorylation. |
TAIR Short Description | KIP-related protein 2 |
TAIR Aliases | ICK2, KRP2 |