Genomics
Overlapping Features
Genome features that overlap coordinates of this Gene
CDSs: 33, Exons: 16, Five Prime UTRs: 5, Gene: 1, mRNAs: 6, Three Prime UTRs: 5, Transposable Element: 1, Transposon Fragment: 1
Proteins
Curated comments from UniProt
Type | Comment | Proteins |
---|---|---|
RPP1_ARATH | function | TIR-NB-LRR receptor-like protein that confers resistance to the pathogen Hyaloperonospora arabidopsis (By similarity). Probably acts as a NAD(+) hydrolase (NADase): in response to activation, catalyzes cleavage of NAD(+) into ADP-D-ribose (ADPR) and nicotinamide; NAD(+) cleavage triggering a defense system that promotes cell death (PubMed:31439792, PubMed:31439793). |
RPP1_ARATH | similarity | Belongs to the disease resistance TIR-NB-LRR family. |
Function
Gene Ontology
cellular component | |
---|---|
endoplasmic reticulum membrane | ECO |
plasma membrane | ECO |
Golgi membrane | ECO |
molecular function | |
ATP binding | ECO |
NAD+ nucleotidase, cyclic ADP-ribose generating | ECO |
LRR domain binding | ECO |
innate immune receptor activity | ECO |
ADP binding | ECO |
NAD+ nucleosidase activity | ECO |
biological process | |
positive regulation of plant-type hypersensitive response | ECO |
defense response | ECO |
response to oomycetes | ECO |
defense response to fungus | ECO |
innate immune response-activating signaling pathway | ECO |
Interactions
Interaction Network
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