DB identifier
|
AT3G25070 | Secondary Identifier
|
locus:2090250 |
| Name
|
RPM1 interacting protein 4 | Brief Description | RPM1 interacting protein 4 |
| TAIR Computational Description | RPM1 interacting protein 4;(source:Araport11) |
| TAIR Curator Summary | Encodes a member of the R protein complex and may represent a virulence target of type III pili effector proteins (virulence factors) from bacterial pathogens, which is 'guarded' by R protein complex (RPM1 and RPS2 proteins). RIN4 physically interacts with RPS2 and RPM1 in vivo. Bacterial avirulence (Avr) effectors AvrB, AvrRpm1, and AvrRpt2 induce a mobility shift in RIN4 and expression of AvrRpt2 induces rapid degradation of RIN4. RIN4 contains 2 sites for AvrRpt2 autocleavage, called RCS1 and RCS2. Overexpression of RIN4 inhibits multiple phenotypes associated with AvrRpt2 function and also inhibits PAMP-induced defense signaling. Attached to the plasma membrane at its carboxyl terminus. Cleaved by AvrRpt2 at two PxFGxW motifs, one releasing a large portion of RIN4 from the plasma membrane and both exposing amino-terminal residues that destabilized the carboxyl-terminal cleavage products by targeting them for N-end ubiquitylation and proteasomal degradation. Major virulence target of the TTSE HopF2Pto. The mRNA is cell-to-cell mobile. |
| TAIR Short Description | RPM1 interacting protein 4 |
| TAIR Aliases | AtRIN4, RIN4 |
Powered by
Have you tried our InterMine mobile apps?
and interoperation is funded by 
