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Gene : PHP A. thaliana

DB identifier  ? AT3G22590 Secondary Identifier  ? locus:2077076
Name  ? PLANT HOMOLOGOUS TO PARAFIBROMIN Brief Description  PLANT HOMOLOGOUS TO PARAFIBROMIN
TAIR Computational Description  PLANT HOMOLOGOUS TO PARAFIBROMIN;(source:Araport11)
TAIR Curator Summary  Encodes PLANT HOMOLOGOUS TO PARAFIBROMIN (PHP), a homolog of human Paf1 Complex (Paf1C) subunit Parafibromin. Human Parafibromin assists in mediating output from the Wnt signaling pathway, and dysfunction of the encoding gene HRPT2 conditions specific cancer-related disease phenotypes. PHP resides in a ~670-kDa protein complex in nuclear extracts, and physically interacts with other known Paf1C-related proteins in vivo. Loss of PHP specifically conditioned accelerated phase transition from vegetative growth to flowering and resulted in misregulation of a very limited subset of genes that included the flowering repressor FLOWERING LOCUS C (FLC). Member of PAF-C complex.
TAIR Short Description  PLANT HOMOLOGOUS TO PARAFIBROMIN
TAIR Aliases  CDC73, PHP

3 Gene Rifs

1 Organism

11 Publications

0 Synonyms

Genomics

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4 Child Features

0 Cross References

1 Downstream Intergenic Region

0 Located Features

1 Upstream Intergenic Region

Proteins

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1 Proteins

Function

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Interactions

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Expression

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Homology

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7 Data Sets