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Gene : ROS4 A. thaliana

DB identifier  ? AT3G14980 Secondary Identifier  ? locus:2086395
Name  ? REPRESSOR OF SILENCING 4 Brief Description  Acyl-CoA N-acyltransferase with RING/FYVE/PHD-type zinc finger protein
TAIR Computational Description  Acyl-CoA N-acyltransferase with RING/FYVE/PHD-type zinc finger protein;(source:Araport11)
TAIR Curator Summary  IDM1 is a histone H3 acetyltransferase that is capable of recognizing methylated DNA through its MBD domain and recognizing unmethylated histone H3K4 through its PHD domain. It negatively regulates DNA demethylation, preventing DNA hypermethylation of highly homologous multicopy genes and other repetitive sequences.
TAIR Short Description  Acyl-CoA N-acyltransferase with RING/FYVE/PHD-type zinc finger protein
TAIR Aliases  IDM1, ROS4

2 Gene Rifs

1 Organism

12 Publications

0 Synonyms

Genomics

Genome feature

Region: gene ? Length: 5714  
Location: Chr3:5039812-5045525 reverse strand

Gene models - ROS4 AT3G14980

? Gene models

Transcripts: 6  Exons: 54  Introns: 48 

Overlapping Features

? Genome features that overlap coordinates of this Gene

25 Child Features

1 Cross References

1 Downstream Intergenic Region

0 Located Features

1 Upstream Intergenic Region

Proteins

Curated comments from UniProt

Type Comment Proteins
IDM1_ARATH function Histone H3 acetyltransferase that binds methylated DNA at chromatin sites lacking histone H3K4 di- or trimethylation and catalyzes H3K18 and H3K23 acetylation (PubMed:22700931, PubMed:22733760). Prevents the transcriptional silencing of transgenes and of some endogenous genes (PubMed:22700931, PubMed:22733760). Requires the presence of IDM2 for efficient H3K18 acetylation, but not for H3K23 acetylation (PubMed:25002145).
IDM1_ARATH subcellular location Colocalizes with IDM2 within nucleoplasmic and nucleolar foci.
IDM1_ARATH tissue specificity Expressed in cotyledons and hypocotyls in young seedlings.

4 Proteins

Function

Gene Ontology

cellular component
plasmodesma  ? ECO  
nucleus  ? ECO  
molecular function
histone acetyltransferase activity  ? ECO  
histone binding  ? ECO  
double-stranded methylated DNA binding  ? ECO  
metal ion binding  ? ECO  
biological process
gene silencing by siRNA-directed DNA methylation  ? ECO  

Interactions

Interaction Network

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Expression

eFP Visualization

Data Source: BAR




Co-expression

Querying ATTED Service...
Data Source: ATTED-II
Top N
LS: LS is a monotonic transformation (negative logit) of MR index. Larger LS indicates stronger co-expression.

 

Homology

Phytozome Homologs

Data Source: Phytozome


0 Homologues

 

Other

9 Data Sets