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Gene : WAG2 A. thaliana

DB identifier  ? AT3G14370 Secondary Identifier  ? locus:2091035
Brief Description  Protein kinase superfamily protein
TAIR Computational Description  Protein kinase superfamily protein;(source:Araport11)
TAIR Curator Summary  The WAG2 and its homolog, WAG1 each encodes protein-serine/threonine kinase that are nearly 70% identical to PsPK3 protein. All three together with CsPK3 belong to PsPK3-type kinases. At the N-terminus, all four possess a serine/threonine-rich domain. They are closely related to Arabidopsis kinases PINOID. wag1/wag2 double mutants exhibit a pronounced wavy root phenotype when grown vertically on agar plates (while wild-type plants develop wavy roots only on plates inclined to angles less than 90 degrees), indicating an overlapping role for WAG1 and WAG2 as suppressors of root waving. Simultaneous disruption of PID(AT2G34650) and its 3 closest homologs (PID2/AT2G26700, WAG1/AT1G53700, and WAG2/AT3G14370) abolishes the formation of cotyledons.
TAIR Short Description  Protein kinase superfamily protein
TAIR Aliases  WAG2

4 Gene Rifs

1 Organism

15 Publications

0 Synonyms

Genomics

Genome feature

Region: gene ? Length: 1785  
Location: Chr3:4797828-4799612 reverse strand

Gene models - WAG2 AT3G14370

? Gene models

Transcripts: 1  Exons: 1 

Overlapping Features

? Genome features that overlap coordinates of this Gene

2 Child Features

0 Cross References

1 Downstream Intergenic Region

0 Located Features

1 Upstream Intergenic Region

Proteins

Curated comments from UniProt

Type Comment Proteins
WAG2_ARATH developmental stage Expressed throughout embryogenesis with higher expression in the cotyledon primordia at heart stages.
WAG2_ARATH function Serine/threonine-protein kinase involved in the regulation of auxin signaling. Acts as a positive regulator of cellular auxin efflux and regulates organ development by enhancing PIN-mediated polar auxin transport. Phosphorylates conserved serine residues in the PIN auxin efflux carriers. Phosphorylation of PIN proteins is required and sufficient for apical-basal PIN polarity that enables directional intercellular auxin fluxes, which mediate differential growth, tissue patterning and organogenesis. Acts as a suppressor of root waving.
WAG2_ARATH similarity Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
WAG2_ARATH subcellular location Targeted to the cell periphery.
WAG2_ARATH tissue specificity Expressed in root tips, lateral root primordia and emerging true leaf primordia.

1 Proteins

Function

Gene Ontology

cellular component
cytosol  ? ECO  
molecular function
ATP binding  ? ECO  
histone H2AS1 kinase activity  ? ECO  
protein serine kinase activity  ? ECO  
kinase activity  ? ECO  
protein serine/threonine kinase activity  ? ECO  
biological process
cotyledon development  ? ECO  
auxin polar transport  ? ECO  
protein phosphorylation  ? ECO  
auxin-activated signaling pathway  ? ECO  

Interactions

Interaction Network

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Expression

eFP Visualization

Data Source: BAR




Co-expression

Querying ATTED Service...
Data Source: ATTED-II
Top N
LS: LS is a monotonic transformation (negative logit) of MR index. Larger LS indicates stronger co-expression.

 

Homology

Phytozome Homologs

Data Source: Phytozome


0 Homologues

 

Other

8 Data Sets