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Gene : VCS A. thaliana

DB identifier  ? AT3G13300 Secondary Identifier  ? locus:2088165
Name  ? VARICOSE Brief Description  Transducin/WD40 repeat-like superfamily protein
TAIR Computational Description  Transducin/WD40 repeat-like superfamily protein;(source:Araport11)
TAIR Curator Summary  Encodes VCS (VARICOSE). Involved in mRNA decapping. VCS forms a mRNA decapping complex with DCP1 (At1g08370) and DCP2 (At5g13570). Unlike DCP2, VCS itself does not have mRNA decapping activity in vitro. DCP1, DCP2 and VCS colocalize in cytoplasmic loci, which are putative Arabidopsis mRNA processing bodies. Null mutants of DCP1, DCP2, and VCS accumulate capped mRNAs with a reduced degradation rate. These mutants also share a similar lethal phenotype at the seedling cotyledon stage, with disorganized veins, swollen root hairs, and altered epidermal cell morphology. VCS is also required for leaf development.
TAIR Short Description  Transducin/WD40 repeat-like superfamily protein
TAIR Aliases  VCS

5 Gene Rifs

1 Organism

24 Publications

0 Synonyms

Genomics

Genome feature

Region: gene ? Length: 6454  
Location: Chr3:4303822-4310275

Gene models - VCS AT3G13300

? Gene models

Transcripts: 3  Exons: 36  Introns: 33 

Overlapping Features

? Genome features that overlap coordinates of this Gene

20 Child Features

1 Cross References

1 Downstream Intergenic Region

0 Located Features

1 Upstream Intergenic Region

Proteins

Curated comments from UniProt

Type Comment Proteins
VCS_ARATH-2 VCS_ARATH developmental stage At early leaf developmental stages, expressed in a spot at the distal end of the organ. As leaf development progresses, present in procambium and differentiating vascular tissues.
VCS_ARATH-2 VCS_ARATH function As a component of the decapping complex, involved in the degradation of mRNAs. Essential for postembryonic development, especially during the formation of the shoot (SAM) and root apical meristems. Required for normal patterning of internal tissues of leaves.
VCS_ARATH-2 A0A1I9LRS8_ARATH VCS_ARATH similarity Belongs to the WD repeat EDC4 family.
VCS_ARATH-2 VCS_ARATH tissue specificity Present in seedlings, roots, hypocotyls, cotyledons, leaves, stems, shoot apex, siliques and flowers. In leaves, particularly present in trichomes, some stomata and vascular tissues.

3 Proteins

Function

Interactions

Interaction Network

Expression

eFP Visualization

Data Source: BAR




Co-expression

Querying ATTED Service...
Data Source: ATTED-II
Top N
LS: LS is a monotonic transformation (negative logit) of MR index. Larger LS indicates stronger co-expression.

 

Homology

Phytozome Homologs

Data Source: Phytozome


0 Homologues

 

Other

9 Data Sets