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Gene : ATSPO11-1 A. thaliana

DB identifier  ? AT3G13170 Secondary Identifier  ? locus:2090044
Brief Description  Spo11/DNA topoisomerase VI, subunit A protein
TAIR Computational Description  Spo11/DNA topoisomerase VI, subunit A protein;(source:Araport11)
TAIR Curator Summary  Encodes AtSPO11-1, one of the three Arabidopsis homologues of the archaeal DNA topoisomerase VIA subunit (topo VIA). Required for meiotic recombination. AtSPO11-1 and AtSPO11-2 have overlapping functions (i.e. both required for meiotic recombination) whereas AtSPO11-3 functions in DNA replication. AtSPO11-1 accumulates in foci in early G2. At 1 h post-S phase, no foci are observed, but by 3 h a majority (80%) of meiocytes at this time point contain >50 foci. However, by 5 h, AtSPO11-1 foci are no longer detectable. This suggests that the protein undergoes a rapid cycle of accumulation and disappearance in meiocytes over a period of between 1 and 5 h post-S phase.
TAIR Short Description  Spo11/DNA topoisomerase VI, subunit A protein
TAIR Aliases  ATSPO11-1, SPO11-1

5 Gene Rifs

1 Organism

22 Publications

0 Synonyms

Genomics

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21 Child Features

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0 Downstream Intergenic Region

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1 Upstream Intergenic Region

Proteins

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2 Proteins

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8 Data Sets