DB identifier | AT3G13170 | Secondary Identifier | locus:2090044 |
Brief Description | Spo11/DNA topoisomerase VI, subunit A protein |
TAIR Computational Description | Spo11/DNA topoisomerase VI, subunit A protein;(source:Araport11) |
TAIR Curator Summary | Encodes AtSPO11-1, one of the three Arabidopsis homologues of the archaeal DNA topoisomerase VIA subunit (topo VIA). Required for meiotic recombination. AtSPO11-1 and AtSPO11-2 have overlapping functions (i.e. both required for meiotic recombination) whereas AtSPO11-3 functions in DNA replication. AtSPO11-1 accumulates in foci in early G2. At 1 h post-S phase, no foci are observed, but by 3 h a majority (80%) of meiocytes at this time point contain >50 foci. However, by 5 h, AtSPO11-1 foci are no longer detectable. This suggests that the protein undergoes a rapid cycle of accumulation and disappearance in meiocytes over a period of between 1 and 5 h post-S phase. |
TAIR Short Description | Spo11/DNA topoisomerase VI, subunit A protein |
TAIR Aliases | ATSPO11-1, SPO11-1 |