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Gene : FAD2 A. thaliana

DB identifier  ? AT3G12120 Secondary Identifier  ? locus:2099297
Name  ? fatty acid desaturase 2 Brief Description  fatty acid desaturase 2
TAIR Computational Description  fatty acid desaturase 2;(source:Araport11)
TAIR Curator Summary  Major enzyme responsible for the synthesis of 18:2 fatty acids in the endoplasmic reticulum. Contains His-rich motifs, which contribute to the interaction with the electron donor cytochrome b5. Mutations in this gene suppress the low temperature-induced phenotype of Arabidopsis tocopherol-deficient mutant vte2.
TAIR Short Description  fatty acid desaturase 2
TAIR Aliases  AtFAD2, FAD2

9 Gene Rifs

1 Organism

66 Publications

0 Synonyms

Genomics

Genome feature

Region: gene ? Length: 3000  
Location: Chr3:3860251-3863250 reverse strand

Gene models - FAD2 AT3G12120

? Gene models

Transcripts: 2  Exons: 4  Introns: 2 

Overlapping Features

? Genome features that overlap coordinates of this Gene

6 Child Features

1 Cross References

1 Downstream Intergenic Region

0 Located Features

1 Upstream Intergenic Region

Proteins

Curated comments from UniProt

Type Comment Proteins
FAD6E_ARATH function ER (microsomal) omega-6 fatty acid desaturase introduces the second double bond in the biosynthesis of 18:3 fatty acids, important constituents of plant membranes (PubMed:14593172, PubMed:7907506). Delta(12)-desaturase with regioselectivity determined by the double bond (delta(9) position) and carboxyl group of the substrate. Can use both 16:1 and 18:1 fatty acids as substrates (PubMed:8685264). It is thought to use cytochrome b5 as an electron donor and to act on fatty acids esterified to phosphatidylcholine (PC) and, possibly, other phospholipids (PubMed:14593172, PubMed:1730697, PubMed:7907506). Very low constitutive hydroxylation activity (PubMed:11864983). Required for desaturation of fatty acids present in extraplastidial membranes, including mitochondria (PubMed:11104757, PubMed:17507388). Required for salt tolerance during seed germination and early seedling growth (PubMed:22279586).
FAD6E_ARATH pathway Lipid metabolism; polyunsaturated fatty acid biosynthesis.
FAD6E_ARATH similarity Belongs to the fatty acid desaturase type 1 family.
FAD6E_ARATH tissue specificity Expressed in shoots and roots (PubMed:22279586, PubMed:7907506). Expressed in leaves, stems, flowers and siliques (PubMed:22279586).

1 Proteins

Function

Interactions

Interaction Network

Expression

eFP Visualization

Data Source: BAR




Co-expression

Querying ATTED Service...
Data Source: ATTED-II
Top N
LS: LS is a monotonic transformation (negative logit) of MR index. Larger LS indicates stronger co-expression.

 

Homology

Phytozome Homologs

Data Source: Phytozome


0 Homologues

 

Other

8 Data Sets