Proteins
Curated comments from UniProt
Type | Comment | Proteins |
---|---|---|
BZP28_ARATH | function | Transcriptional activator involved in ER stress responses. Functions as a stress sensor and transducer in ER stress signaling pathway. After proteolysis by SBT6.1 (S1P) and S2P, the N-terminal bZIP component is translocated to the nucleus, where it activates the expression and production of ER chaperones (PubMed:18156219, PubMed:18634751, PubMed:18849477, PubMed:20876872). Following ER stress, activates proteins involved in brassinosteroid (BR) signaling, which is required for stress acclimation and growth (PubMed:20876872). |
BZP28_ARATH | similarity | Belongs to the bZIP family. |
BZP28_ARATH | subcellular location | Translocates to the nucleus following heat shock or tunicamycin treatment (ER stress) (PubMed:18156219, PubMed:18634751, PubMed:18849477, PubMed:20876872, PubMed:22335396, PubMed:23558471, PubMed:23624714). Relocation of BZIP28 from ER to the nucleus occurs through the Golgi and is S2P-dependent (PubMed:20876872, PubMed:22335396, PubMed:23558471, PubMed:23624714). |
Function
Gene Ontology
cellular component | |
---|---|
endoplasmic reticulum | ECO |
endoplasmic reticulum membrane | ECO |
nuclear envelope | ECO |
perinuclear region of cytoplasm | ECO |
nucleus | ECO |
nucleoplasm | ECO |
membrane | ECO |
Golgi membrane | ECO |
cytoplasm | ECO |
molecular function | |
DNA-binding transcription factor activity | ECO |
DNA binding | ECO |
biological process | |
response to heat | ECO |
response to endoplasmic reticulum stress | ECO |
endoplasmic reticulum unfolded protein response | ECO |
response to unfolded protein | ECO |
Interactions
Interaction Network
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