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LOSS OF GIANT CELLS FROM ORGANS;(source:Araport11)
TAIR Curator Summary
Encodes LGO (loss of giant cells from organs) required for endoreduplication in sepal giant cell formation. Giant cells in both leaves and sepals are absent in lgo mutants. LGO is a member of a plant specific cell cycle inhibitor family SIAMESE and was originally named as SMR1(SIAMESE RELATED 1).
Probable cyclin-dependent protein kinase (CDK) inhibitor that functions as a repressor of mitosis in the endoreduplication cell cycle (PubMed:17098811, PubMed:26546445). Cooperates with SIM and SMR2 to promote endoreplication during leaf development (PubMed:26546445). Specifically regulates endoreduplication in epidermal pavement cells to produce the cell size pattern (PubMed:20485493). Is necessary for giant cell formation (PubMed:20485493). Positive regulator of effector-triggered immunity (ETI) (PubMed:25455564).