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Gene : RGLG1 A. thaliana

DB identifier  ? AT3G01650 Secondary Identifier  ? locus:2084218
Name  ? RING domain ligase1 Brief Description  RING domain ligase1
TAIR Computational Description  RING domain ligase1;(source:Araport11)
TAIR Curator Summary  Encodes RGLG1 (RING domain ligase 1), a RING domain ubiquitin E3 ligase that negatively regulates the drought stress response by mediating ERF53 transcriptional activity. ABA inhibits myristoylation and induces shuttling of the RGLG1 to promote nuclear degradation of PP2CA.
TAIR Short Description  RING domain ligase1
TAIR Aliases  RGLG1

2 Gene Rifs

1 Organism

18 Publications

0 Synonyms

Genomics

Genome feature

Region: gene ? Length: 3546  
Location: Chr3:241739-245284

Gene models - RGLG1 AT3G01650

? Gene models

Transcripts: 2  Exons: 22  Introns: 20 

Overlapping Features

? Genome features that overlap coordinates of this Gene

15 Child Features

1 Cross References

1 Downstream Intergenic Region

0 Located Features

1 Upstream Intergenic Region

Proteins

Curated comments from UniProt

Type Comment Proteins
RGLG1_ARATH function E3 ubiquitin-protein ligase that mediates the formation of 'Lys-63'-linked ubiquitin chains. Regulates apical dominance by acting on the auxin transport proteins abundance (PubMed:17586653). Together with RGLG5, mediates the ubiquitination and subsequent proteasomal degradation of the target protein PP2CA. Functions as a positive regulator of abscisic acid (ABA) signaling through ABA-dependent degradation of PP2CA, a major inhibitor of ABA signaling (PubMed:27577789). Acts as a negative regulator of drought stress response (PubMed:22095047).
RGLG1_ARATH tissue specificity Ubiquitously expressed.

1 Proteins

Function

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Interactions

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Expression

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Homology

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0 Homologues

 

Other

8 Data Sets