help  | faq  | software  | BAR
Hide

Oops!

https://bar.utoronto.ca/thalemine/service/ is incorrect
Hide

Oops!

Error: 403
Hide Your session has expired. If you were not logged in, your data (including query history and any lists you made) has been cleared.Your session has expired. If you were not logged in, your data (including query history and any lists you made) has been cleared.

Gene : AT2G42670 A. thaliana

DB identifier  ? AT2G42670 Secondary Identifier  ? locus:2041524
Brief Description  2-aminoethanethiol dioxygenase, putative (DUF1637)
TAIR Computational Description  2-aminoethanethiol dioxygenase, putative (DUF1637);(source:Araport11)
TAIR Curator Summary  Plant Cysteine Oxidase (PCO). Involved in controlling the stability of Group VII ethylene response factors (ERF-VIIs) via N-Arg/degron pathway through catalyzing the oxidation of their N-Cys for subsequent Arginyl-tRNA--protein transferase 1 (ATE1) mediated arginine installation.
TAIR Short Description  Protein of unknown function (DUF1637)
TAIR Aliases  PCO4

1 Gene Rifs

1 Organism

11 Publications

0 Synonyms

Genomics

Genome feature

Region: gene ? Length: 2951  
Location: Chr2:17771697-17774647 reverse strand

Gene models - AT2G42670 AT2G42670

? Gene models

Transcripts: 3  Exons: 17  Introns: 14 

Overlapping Features

? Genome features that overlap coordinates of this Gene

12 Child Features

0 Cross References

1 Downstream Intergenic Region

0 Located Features

1 Upstream Intergenic Region

Proteins

Curated comments from UniProt

Type Comment Proteins
PCO4_ARATH PCO4_ARATH-2 function Catalyzes the oxidation of N-terminal cysteine residues (N-Cys), thus preparing the protein for N-end rule pathway-mediated proteasomal degradation, upstream of the N-end rule enzymes ATE1, ATE2 and PRT6 (Probable) (PubMed:28332493, PubMed:29848548, PubMed:32868422, PubMed:33207269). Controls the preparation of the group VII ethylene response factor (ERF-VII) proteins for degradation via the 26S proteasome N-end rule pathway (Probable) (PubMed:28332493, PubMed:29848548, PubMed:32868422, PubMed:33207269). Acts as an oxygen sensor that controls the stability of ERF-VII proteins, which are stabilized in flooding-induced hypoxia, and regulate transcriptional adaptation to these adverse conditions (PubMed:28332493, PubMed:29848548).
A0A1P8B2S7_ARATH PCO4_ARATH PCO4_ARATH-2 A0A178VN46_ARATH similarity Belongs to the cysteine dioxygenase family.

4 Proteins

Function

Gene Ontology

cellular component
nucleus  ? ECO  
cytoplasm  ? ECO  
molecular function
cysteine dioxygenase activity  ? ECO  
iron ion binding  ? ECO  
biological process
detection of hypoxia  ? ECO  
peptidyl-cysteine oxidation  ? ECO  
cellular response to hypoxia  ? ECO  

Interactions

Interaction Network

Show the following interaction types:
Reset view
Show in table format
Export graph

Click on a gene to get more info about it.

Expression

eFP Visualization

Data Source: BAR




Co-expression

Querying ATTED Service...
Data Source: ATTED-II
Top N
LS: LS is a monotonic transformation (negative logit) of MR index. Larger LS indicates stronger co-expression.

 

Homology

Phytozome Homologs

Data Source: Phytozome


0 Homologues

 

Other

7 Data Sets