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Gene : GRL A. thaliana

DB identifier  ? AT2G35110 Secondary Identifier  ? locus:2063479
Name  ? GNARLED Brief Description  transcription activator
TAIR Computational Description  transcription activator;(source:Araport11)
TAIR Curator Summary  Component of the WAVE protein complex which act as activators of ARP2/3 complex involved in actin nucleation. Required for trichome morphogenesis. Mutant displays distorted trichomes, a phenotype that can be phenocopied by treatment of WT plants with actin-interacting drugs. Its ER localization is independent of upstream SPK1 activation signaling and the physical association with the WAVE/SCAR Regulatory complex binding partner SRA1. ER-localized NAP1 has little colocalization with actin and represent the inactive pool of NAP1 in these cell types. Suppresses ETI triggered cell death by interactions with translational machinery. Reference gene model updated to AT2G35110.2 (PMID:36797349)
TAIR Short Description  transcription activators
TAIR Aliases  GRL, HEM1, LPL3, NAP1, NAPP

7 Gene Rifs

1 Organism

30 Publications

0 Synonyms

Genomics

Genome feature

Region: gene ? Length: 8257  
Location: Chr2:14795715-14803971 reverse strand

Gene models - GRL AT2G35110

? Gene models

Transcripts: 2  Exons: 45  Introns: 43 

Overlapping Features

? Genome features that overlap coordinates of this Gene

27 Child Features

1 Cross References

1 Downstream Intergenic Region

0 Located Features

1 Upstream Intergenic Region

Proteins

Curated comments from UniProt

Type Comment Proteins
NCKP1_ARATH NCKP1_ARATH-2 function Involved in regulation of actin and microtubule organization. Part of a WAVE complex that activates the Arp2/3 complex.
NCKP1_ARATH NCKP1_ARATH-2 A0A178W190_ARATH similarity Belongs to the HEM-1/HEM-2 family.
NCKP1_ARATH NCKP1_ARATH-2 tissue specificity Expressed in roots, root hairs, hypocotyls, cotyledons, stems, leaves, trichomes, and flowers.

3 Proteins

Function

Gene Ontology

cellular component
endoplasmic reticulum membrane  ? ECO  
nucleus  ? ECO  
SCAR complex  ? ECO  
molecular function
No terms in this category.
biological process
actin filament organization  ? ECO  
positive regulation of DNA-templated transcription  ? ECO  
multidimensional cell growth  ? ECO  
trichome morphogenesis  ? ECO  
actin nucleation  ? ECO  

Interactions

Interaction Network

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Expression

eFP Visualization

Data Source: BAR




Co-expression

Querying ATTED Service...
Data Source: ATTED-II
Top N
LS: LS is a monotonic transformation (negative logit) of MR index. Larger LS indicates stronger co-expression.

 

Homology

Phytozome Homologs

Data Source: Phytozome


0 Homologues

 

Other

9 Data Sets