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Gene : AT2G32760 A. thaliana

DB identifier  ? AT2G32760 Secondary Identifier  ? locus:2046362
Brief Description  UV radiation resistance-associated protein
TAIR Computational Description  UV radiation resistance-associated protein;(source:Araport11)
TAIR Curator Summary  Homolog of yeast VPS38P. Interacts with PI3K.Mutants have defects in late endosome morphology and retromer function.
TAIR Short Description  NULL
TAIR Aliases  USL1, VPS38

2 Gene Rifs

1 Organism

7 Publications

0 Synonyms

Genomics

Genome feature

Region: gene ? Length: 3231  
Location: Chr2:13891537-13894767

Gene models - AT2G32760 AT2G32760

? Gene models

Transcripts: 3  Exons: 17  Introns: 14 

Overlapping Features

? Genome features that overlap coordinates of this Gene

11 Child Features

0 Cross References

1 Downstream Intergenic Region

0 Located Features

1 Upstream Intergenic Region

Proteins

Curated comments from UniProt

Type Comment Proteins
VPS38_ARATH developmental stage Strongly expressed in nascent leaves and, as leaves grow, progressively restricted to the vasculatures, leaves tips and hydathodes along leaves margins (PubMed:29897620). In roots, accumulates in the tips, vasculatures and lateral root initiation sites (PubMed:29897620). In flowers, present in anthers, pollen and pistils (PubMed:29897620).
VPS38_ARATH function Dispensable for autophagy but essential for efficient targeting and degradation of biosynthetic and endocytic cargo to the vacuole (PubMed:29184027). Required for seedling development and plant growth as well as for seed storage proteins (SSPs) vacuolar trafficking (PubMed:29184027). Controls multiple aspects of development by affecting late endosome morphology and by regulating vacuolar and endocytic cargos (e.g PIN1 and PIN2) trafficking and distributions (e.g. polarity), thus influencing auxin transport orientation (PubMed:29184027, PubMed:29897620).
VPS38_ARATH subcellular location Colocalizes with and mobilizes VPS29 at late endosomes, probably in a PI3K complex-dependent manner.
VPS38_ARATH tissue specificity Predominantly expressed in the shoot apical meristem (SAM) and in the leaf vascular tissues (PubMed:29897620). Also observed in roots, pollen and flowers (PubMed:29897620).

2 Proteins

Function

Interactions

Interaction Network

Expression

eFP Visualization

Data Source: BAR




Co-expression

Querying ATTED Service...
Data Source: ATTED-II
Top N
LS: LS is a monotonic transformation (negative logit) of MR index. Larger LS indicates stronger co-expression.

 

Homology

Phytozome Homologs

Data Source: Phytozome


0 Homologues

 

Other

7 Data Sets