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Gene : EME1A A. thaliana

DB identifier  ? AT2G21800 Secondary Identifier  ? locus:2052484
Name  ? essential meiotic endonuclease 1A Brief Description  essential meiotic endonuclease 1A
TAIR Computational Description  essential meiotic endonuclease 1A;(source:Araport11)
TAIR Curator Summary  Forms a complex with MUS81 that functions as endonuclease in DNA recombination and repair processes.
TAIR Short Description  essential meiotic endonuclease 1A
TAIR Aliases  ATEME1A, EME1A

1 Gene Rifs

1 Organism

6 Publications

0 Synonyms

Genomics

Genome feature

Region: gene ? Length: 3849  
Location: Chr2:9298078-9301926

Gene models - EME1A AT2G21800

? Gene models

Transcripts: 3  Exons: 35  Introns: 32 

Overlapping Features

? Genome features that overlap coordinates of this Gene

21 Child Features

0 Cross References

1 Downstream Intergenic Region

0 Located Features

1 Upstream Intergenic Region

Proteins

Curated comments from UniProt

Type Comment Proteins
EME1A_ARATH-2 EME1A_ARATH function Interacts with MUS81 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, D-loops, replication forks, nicked Holliday junctions and also intact Holliday junctions with a reduced efficiency. May be required in mitosis for the processing of stalled or collapsed replication fork intermediates. Plays a role in DNA repair and in genotoxic stress-induced homologous recombination (HR) in somatic cells. Mediates a subset of meiotic recombination events that are insensitive to crossover interference.
A0A1P8AYE0_ARATH EME1A_ARATH-2 EME1A_ARATH similarity Belongs to the EME1/MMS4 family.

3 Proteins

Function

Gene Ontology

cellular component
Holliday junction resolvase complex  ? ECO  
nucleus  ? ECO  
molecular function
metal ion binding  ? ECO  
DNA binding  ? ECO  
endonuclease activity  ? ECO  
biological process
DNA recombination  ? ECO  
cell division  ? ECO  
meiotic cell cycle  ? ECO  
DNA repair  ? ECO  

Interactions

Interaction Network

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Expression

eFP Visualization

Data Source: BAR




Co-expression

Querying ATTED Service...
Data Source: ATTED-II
Top N
LS: LS is a monotonic transformation (negative logit) of MR index. Larger LS indicates stronger co-expression.

 

Homology

Phytozome Homologs

Data Source: Phytozome


0 Homologues

 

Other

7 Data Sets