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Gene : AT2G21120 A. thaliana

DB identifier  ? AT2G21120 Secondary Identifier  ? locus:2047112
Brief Description  magnesium transporter, putative (DUF803)
TAIR Computational Description  magnesium transporter, putative (DUF803);(source:Araport11)
TAIR Curator Summary  Encodes a putative magnesium transporter that was identified through a forward genetic screen, directly isolating antiviral RNAi-defective (avi) mutant using a Cucumber Mosaic Virus (CMV) mutant. Compared to Wildtype Col-0, avi2 mutant showed severe disease symptom after viral infection and viral accumulation was significantly increased while viral siRNAs and virus-activated endogenous siRNAs (vasiRNAs) were reduced in avi2 mutant. Detailed genetic study indicated that AVI2 modulated RNAi-mediated antiviral immunity by regulating the biogenesis of secondary viral siRNAs and vasiRNAs in Arabidopsis.
TAIR Short Description  Protein of unknown function (DUF803)
TAIR Aliases  AVI2, ENOR3

2 Gene Rifs

1 Organism

7 Publications

0 Synonyms

Genomics

Genome feature

Region: gene ? Length: 3097  
Location: Chr2:9051725-9054821 reverse strand

Gene models - AT2G21120 AT2G21120

? Gene models

Transcripts: 1  Exons: 9  Introns: 8 

Overlapping Features

? Genome features that overlap coordinates of this Gene

10 Child Features

0 Cross References

1 Downstream Intergenic Region

0 Located Features

1 Upstream Intergenic Region

Proteins

Curated comments from UniProt

Type Comment Proteins
NIPA6_ARATH function Acts as a Mg(2+) transporter. Can also transport other divalent cations such as Fe(2+), Sr(2+), Ba(2+), Mn(2+) and Co(2+) but to a much less extent than Mg(2+) (By similarity).
NIPA6_ARATH similarity Belongs to the NIPA (TC 2.A.7) family.
NIPA6_ARATH subcellular location Recruited to the cell membrane in response to low extracellular magnesium.

1 Proteins

Function

Gene Ontology

cellular component
endoplasmic reticulum  ? ECO  
plasma membrane  ? ECO  
membrane  ? ECO  
early endosome  ? ECO  
molecular function
magnesium ion transmembrane transporter activity  ? ECO  
protein self-association  ? ECO  
biological process
defense response to virus  ? ECO  
magnesium ion transport  ? ECO  

Interactions

Interaction Network

Expression

eFP Visualization

Data Source: BAR




Co-expression

Querying ATTED Service...
Data Source: ATTED-II
Top N
LS: LS is a monotonic transformation (negative logit) of MR index. Larger LS indicates stronger co-expression.

 

Homology

Phytozome Homologs

Data Source: Phytozome


0 Homologues

 

Other

7 Data Sets