help  | faq  | software  | BAR
Hide

Oops!

Error: 403

Gene : SYTA A. thaliana

DB identifier  ? AT2G20990 Secondary Identifier  ? locus:2047057
Name  ? synaptotagmin A Brief Description  synaptotagmin A
TAIR Computational Description  synaptotagmin A;(source:Araport11)
TAIR Curator Summary  Encodes a protein specifically localized to the ER-PM boundary with similarity to synaptotagmins, a class of membrane trafficking proteins. SYT1 is expressed in all tissues. Loss of function mutations show hypersensitivity to NaCl and electrolyte leakage from the plasma membrane. SYT1 also affects calcium dependent freezing tolerance and mechanical stress response. Regulates endocytosis endosome recycling at the plasma membrane, but not membrane traffic along the secretory pathway. SYT1 may have a role in membrane repair such as membrane resealing after freezing induced damage. SYT1 binds to phosphatidylinositol phosphates in vitro. It is distributed to immobile tubules and likely plays an important role in the formation of the tubular ER network as well as in cellular ER-PM tethering.
TAIR Short Description  synaptotagmin A
TAIR Aliases  AtSYT1, ATSYTA, NTMC2T1.1, NTMC2TYPE1.1, SYT1, SYTA

14 Gene Rifs

1 Organism

29 Publications

0 Synonyms

Genomics

Genome feature

Region: gene ? Length: 3630  
Location: Chr2:9014470-9018099

Gene models - SYTA AT2G20990

? Gene models

Transcripts: 3  Exons: 33  Introns: 30 

Overlapping Features

? Genome features that overlap coordinates of this Gene

19 Child Features

1 Cross References

1 Downstream Intergenic Region

0 Located Features

1 Upstream Intergenic Region

Proteins

Curated comments from UniProt

Type Comment Proteins
SYT1_ARATH function Plays an important role in maintaining plasma membrane integrity during freezing and osmotic stresses. May function in membrane resealing during calcium-dependent freezing tolerance. May regulate endocytosis and endosome recycling at the plasma membrane and cell-to-cell trafficking of cabbage leaf curl virus (CaLCuV) and tobacco mosaic virus (TMV) movement proteins via plasmodesmata.
SYT1_ARATH F4IFM6_ARATH F4IFM7_ARATH similarity Belongs to the synaptotagmin family.
SYT1_ARATH tissue specificity Expressed in roots, shoots, rosette and cauline leaves, inflorescences, and siliques. In roots, expressed in vascular bundle, epidermis, the differential zone of the tips of root hairs, and the quiescent center and columella of root tips.

3 Proteins

Function

Gene Ontology

cellular component
endoplasmic reticulum  ? ECO  
plasma membrane  ? ECO  
endosome membrane  ? ECO  
molecular function
lipid binding  ? ECO  
metal ion binding  ? ECO  
biological process
lipid transport  ? ECO  
endocytosis  ? ECO  

Interactions

Interaction Network

Show the following interaction types:
Reset view
Show in table format
Export graph

Click on a gene to get more info about it.

Expression

eFP Visualization

Data Source: BAR




Co-expression

Querying ATTED Service...
Data Source: ATTED-II
Top N
LS: LS is a monotonic transformation (negative logit) of MR index. Larger LS indicates stronger co-expression.

 

Homology

Phytozome Homologs

Data Source: Phytozome


0 Homologues

 

Other

9 Data Sets