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Gene : ALD1 A. thaliana

DB identifier  ? AT2G13810 Secondary Identifier  ? locus:2040481
Name  ? AGD2-like defense response protein 1 Brief Description  AGD2-like defense response protein 1
TAIR Computational Description  AGD2-like defense response protein 1;(source:Araport11)
TAIR Curator Summary  ALD1 is a L-lysine alpha-aminotransferase. It is part of the pipecolic acid biosynthetic pathway, where it catalyzes the biochemical conversion of lysine to epsilon-amino-alpha-ketocaproic acid (KAC) which is subject to subsequent transamination, cyclization and isomerization to form 2,3-dehydropipecolic acid.
TAIR Short Description  AGD2-like defense response protein 1
TAIR Aliases  ALD1, AtALD1, EDTS5

8 Gene Rifs

1 Organism

23 Publications

0 Synonyms

Genomics

Genome feature

Region: gene ? Length: 3850  
Location: Chr2:5768417-5772266

Gene models - ALD1 AT2G13810

? Gene models

Transcripts: 1  Exons: 10  Introns: 9 

Overlapping Features

? Genome features that overlap coordinates of this Gene

11 Child Features

0 Cross References

1 Downstream Intergenic Region

0 Located Features

1 Upstream Intergenic Region

Proteins

Curated comments from UniProt

Type Comment Proteins
ALD1_ARATH function Aminotransferase involved in local and systemic acquired resistance (SAR) to the bacterial pathogen P.syringae. Required for salicylic acid (SA) and camalexin accumulation upon pathogen infection. Possesses aminotransferase activity in vitro and may generate amino-acid-derived defense signals in vivo. May be involved in ethylene-induced senescence signaling. Involved in the biosynthesis of pipecolate (Pip), a metabolite that orchestrates defense amplification, positive regulation of SA biosynthesis, and priming to guarantee effective local resistance induction and the establishment of SAR (PubMed:23221596, PubMed:27758894). Converts lysine to alpha-keto-epsilon-aminocaproate, which then can spontaneously cyclize to form delta-(1)-piperideine-2-carboxylate (P2C). P2C is converted to Pip by SARD4 (PubMed:27758894). May produce non-Pip metabolites that play roles in immunity. Involved in the synthesis of distinct metabolite signals that affect basal and early defenses, and later defense responses (PubMed:25372120).
ALD1_ARATH similarity Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily.
ALD1_ARATH tissue specificity Highly expressed in senescing leaves, flowers, siliques and seeds.

1 Proteins

Function

Interactions

Interaction Network

Expression

eFP Visualization

Data Source: BAR




Co-expression

Querying ATTED Service...
Data Source: ATTED-II
Top N
LS: LS is a monotonic transformation (negative logit) of MR index. Larger LS indicates stronger co-expression.

 

Homology

Phytozome Homologs

Data Source: Phytozome


0 Homologues

 

Other

7 Data Sets