DB identifier
|
AT1G78870 | Secondary Identifier
|
locus:2037553 |
| Name
|
ubiquitin-conjugating enzyme 35 | Brief Description | ubiquitin-conjugating enzyme 35 |
| TAIR Computational Description | ubiquitin-conjugating enzyme 35;(source:Araport11) |
| TAIR Curator Summary | UBC35/UBC13A encodes a protein that may play a role in DNA damage responses and error-free post-replicative DNA repair by participating in lysine-63-based polyubiquitination reactions. UBC35/UBC13A can form diubiquitin and triubiquitin chains in combination with MMZ1,2,3,4/(UEV1A,B,C,D) in vitro. It can also functionally complement an mms2 ubc13 mutation in budding yeast by increasing the double mutant's viability in the presence of the DNA damaging agent MMS, when it is co-expressed with MMZ / UEV1 genes. A wild type phenotype is restored with MMZ3/UEV1C and MMZ4/UEV1D, but only partial complementation is achieved with MMZ1/UEV1A or MMZ2/UEV1B. The mRNA is cell-to-cell mobile. |
| TAIR Short Description | ubiquitin-conjugating enzyme 35 |
| TAIR Aliases | UBC13A, UBC35 |
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