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Gene : GGH1 A. thaliana

DB identifier  ? AT1G78660 Secondary Identifier  ? locus:2037583
Name  ? gamma-glutamyl hydrolase 1 Brief Description  gamma-glutamyl hydrolase 1
TAIR Computational Description  gamma-glutamyl hydrolase 1;(source:Araport11)
TAIR Curator Summary  The Arabidopsis protein AtGGH1 is a gamma-glutamyl hydrolase cleaving pentaglutamates to yield di- and triglutamates. The enzyme is involved in the tetrahydrofolate metabolism and located to the vacuole.
TAIR Short Description  gamma-glutamyl hydrolase 1
TAIR Aliases  ATGGH1, GGH1

0 Gene Rifs

1 Organism

8 Publications

0 Synonyms

Genomics

Genome feature

Region: gene ? Length: 2713  
Location: Chr1:29585677-29588389

Gene models - GGH1 AT1G78660

? Gene models

Transcripts: 3  Exons: 33  Introns: 30 

Overlapping Features

? Genome features that overlap coordinates of this Gene

18 Child Features

0 Cross References

1 Downstream Intergenic Region

0 Located Features

1 Upstream Intergenic Region

Proteins

Curated comments from UniProt

Type Comment Proteins
GGH1_ARATH GGH1_ARATH-2 function Cleaves the polyglutamate sidechains of folate polyglutamates in the vacuole. Is important for polyglutamyl tail length determination before vacuolar exit. Plays a role in folate stability and intracellular folate content.
GGH1_ARATH GGH1_ARATH-2 A0A5S9WVI3_ARATH similarity Belongs to the peptidase C26 family.
GGH1_ARATH GGH1_ARATH-2 subcellular location Extracellular or cell-wall bound.
GGH1_ARATH GGH1_ARATH-2 tissue specificity Highly expressed in roots and at lower levels in leaves, stems and siliques.

3 Proteins

Function

Gene Ontology

cellular component
extracellular region  ? ECO  
vacuole  ? ECO  
molecular function
omega peptidase activity  ? ECO  
gamma-glutamyl-peptidase activity  ? ECO  
biological process
tetrahydrofolylpolyglutamate metabolic process  ? ECO  

Interactions

Interaction Network

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Expression

eFP Visualization

Data Source: BAR




Co-expression

Querying ATTED Service...
Data Source: ATTED-II
Top N
LS: LS is a monotonic transformation (negative logit) of MR index. Larger LS indicates stronger co-expression.

 

Homology

Phytozome Homologs

Data Source: Phytozome


0 Homologues

 

Other

6 Data Sets