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Gene : MIF1 A. thaliana
DB identifier  ? AT1G74660 Secondary Identifier  ? locus:2019190
Name  ? mini zinc finger 1 Brief Description  mini zinc finger 1
TAIR Computational Description  mini zinc finger 1;(source:Araport11)
TAIR Curator Summary  Encodes MINI ZINC FINGER 1 (MIF1) which has a zinc finger domain but lacks other protein motifs normally present in transcription factors. MIF1 physically interact with a group of zinc finger-homeodomain (ZHD) transcription factors, such as ZHD5 (AT1G75240), that regulate floral architecture and leaf development. Gel mobility shift assays revealed that MIF1 blocks the DNA binding activity of ZHD5 homodimers by competitively forming MIF1-ZHD5 heterodimers. Constitutive overexpression of MIF1 caused dramatic developmental defects, seedlings were non-responsive to gibberellin (GA) for cell elongation, hypersensitive to the GA synthesis inhibitor paclobutrazol (PAC) and abscisic acid (ABA), and hyposensitive to auxin, brassinosteroid and cytokinin, but normally responsive to ethylene.
TAIR Short Description  mini zinc finger 1
TAIR Aliases  MIF1
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4 Gene Rifs

1 Organism

11 Publications

0 Synonyms

Genomics

Genome feature

Region: gene ? Length: 2818  
Location: Chr1:28045472-28048289 reverse strand

Gene models - MIF1 AT1G74660

? Gene models

Transcripts: 2  Exons: 3  Introns: 1 

Overlapping Features

? Genome features that overlap coordinates of this Gene

CDSs: 3, Exons: 5, Five Prime UTRs: 2, Genes: 2, Lnc RNAs: 2, mRNAs: 2, Three Prime UTRs: 2
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5 Child Features

1 Cross References

0 Downstream Intergenic Region

0 Located Features

1 Upstream Intergenic Region

Proteins

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Curated comments from UniProt

Type Comment Proteins
MIF1_ARATH function Inhibits zinc finger homeodomain (ZHD) transcription factors, such as ZHD5, by interacting with them to prevent both their nuclear localization and their DNA-binding properties. Involved in integrating signals from multiple hormones by preventing the expression of genes involved in gibberellic acid (GA), auxin and brassinosteroid signaling and by promoting the expression of abscisic acid (ABA)-responsive genes. Regulates several development aspects, including photomorphogenesis, apical dominance, longevity, flower morphology and fertility, as well as root and stem elongation. Promotes the formation of ectopic shoot meristems on leaf margins.
MIF1_ARATH tissue specificity Mostly expressed in roots and stems, present in siliques and seedlings, and weakly observed in petioles, leaves and flowers.

2 Proteins

Function

Interactions

Interaction Network

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Expression

eFP Visualization

Data Source: BAR




Co-expression

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Data Source: ATTED-II
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Homology

Phytozome Homologs

Data Source: Phytozome


0 Homologues

 

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9 Data Sets






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