Proteins
Curated comments from UniProt
Type | Comment | Proteins |
---|---|---|
MMD1_ARATH | developmental stage | First detected in sporogenous cells at late anther stage 4. Maximum levels observed in male meiocytes at anther stage 5, prior to meiosis. Fades out at anther stage 6, during meiosis to disappear later. Also present at low levels in the placenta of very young pistils. |
MMD1_ARATH | function | Probable transcription factor required for chromosome organization and progression during male meiosis (e.g. microsporogenesis) (PubMed:12782723, PubMed:14573517). Necessary for fertility and meiotic progressive compaction of prophase I chromosomes to metaphase I bivalents (PubMed:27385818). Together with JMJ16, promotes gene expression in male meiocytes in an H3K9me3-dependent manner, and contributes to meiotic chromosome condensation by triggering some condensin promoters (e.g. CAP-D3 and CAP-H) (PubMed:27385818, PubMed:32572214). |
MMD1_ARATH | tissue specificity | Expressed in inflorescence, specifically in male meiocytes. |
Function
Gene Ontology
cellular component | |
---|---|
nucleus | ECO |
euchromatin | ECO |
molecular function | |
sequence-specific DNA binding | ECO |
histone binding | ECO |
DNA binding | ECO |
transcription cis-regulatory region binding | ECO |
metal ion binding | ECO |
euchromatin binding | ECO |
biological process | |
male meiotic nuclear division | ECO |
positive regulation of chromosome condensation | ECO |
pollen sperm cell differentiation | ECO |
positive regulation of gene expression | ECO |
regulation of DNA-templated transcription | ECO |
male meiosis chromosome segregation | ECO |
meiotic cell cycle | ECO |
meiotic spindle organization | ECO |
meiotic chromosome condensation | ECO |