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Gene : MDO1 A. thaliana

DB identifier  ? AT1G56260 Secondary Identifier  ? locus:2011781
Name  ? MERISTEM DISORGANIZATION 1 Brief Description  telomere-capping, CST complex subunit
TAIR Computational Description  telomere-capping, CST complex subunit;(source:Araport11)
TAIR Curator Summary  Required for the maintenance of stem cells through a reduction in DNA damage.
TAIR Short Description  NULL
TAIR Aliases  MDO1, TEN1

3 Gene Rifs

1 Organism

8 Publications

0 Synonyms

Genomics

Genome feature

Region: gene ? Length: 1653  
Location: Chr1:21064223-21065875 reverse strand

Gene models - MDO1 AT1G56260

? Gene models

Transcripts: 2  Exons: 7  Introns: 5 

Overlapping Features

? Genome features that overlap coordinates of this Gene

7 Child Features

0 Cross References

1 Downstream Intergenic Region

0 Located Features

1 Upstream Intergenic Region

Proteins

Curated comments from UniProt

Type Comment Proteins
TEN1_ARATH function Required for the maintenance of meristems and stem cells through the reduction of DNA damage (PubMed:21781195). Promotes telomere integrity by maintaining telomere length and proper architecture of the chromosome terminus (PubMed:23572541). Negatively regulates telomerase repeat addition processivity (PubMed:23572541). Hampers contacts between enzymatically active telomerase and CST complex (PubMed:25329641).
TEN1_ARATH similarity Belongs to the TEN1 family.
TEN1_ARATH subcellular location Associates transiently with telomeres.
TEN1_ARATH tissue specificity Ubiquitous (PubMed:21781195, PubMed:23572541). High expression in meristematic tissues and in vasculature (PubMed:21781195).

1 Proteins

Function

Gene Ontology

cellular component
chromosome, telomeric region  ? ECO  
CST complex  ? ECO  
molecular function
telomerase inhibitor activity  ? ECO  
single-stranded DNA binding  ? ECO  
protein folding chaperone  ? ECO  
biological process
response to heat  ? ECO  
stem cell population maintenance  ? ECO  
telomere maintenance  ? ECO  
shoot system development  ? ECO  

Interactions

Interaction Network

Expression

eFP Visualization

Data Source: BAR




Co-expression

Querying ATTED Service...
Data Source: ATTED-II
Top N
LS: LS is a monotonic transformation (negative logit) of MR index. Larger LS indicates stronger co-expression.

 

Homology

Phytozome Homologs

Data Source: Phytozome


0 Homologues

 

Other

7 Data Sets