help  | faq  | software  | BAR
Hide

Oops!

Error: 403

Gene : AT1G48360 A. thaliana

DB identifier  ? AT1G48360 Secondary Identifier  ? locus:2007740
Brief Description  zinc ion binding/nucleic acid binding/hydrolase
TAIR Computational Description  zinc ion binding/nucleic acid binding/hydrolase;(source:Araport11)
TAIR Curator Summary  Encodes a FAN1 homolog that is involved in interstrand crosslink repair. FAN1 appears to act in in a different pathway from MUS81 but in similar pathway with RECQ4A, RAD5A and MFH1.
TAIR Short Description  zinc ion binding;nucleic acid binding;hydrolases, acting on acid anhydrides, in phosphorus-containing anhydrides
TAIR Aliases  FAN1

0 Gene Rifs

1 Organism

9 Publications

0 Synonyms

Genomics

Genome feature

Region: gene ? Length: 4740  
Location: Chr1:17868522-17873261

Gene models - AT1G48360 AT1G48360

? Gene models

Transcripts: 6  Exons: 83  Introns: 77 

Overlapping Features

? Genome features that overlap coordinates of this Gene

31 Child Features

1 Cross References

1 Downstream Intergenic Region

0 Located Features

0 Upstream Intergenic Region

Proteins

Curated comments from UniProt

Type Comment Proteins
A0A1P8AVS5_ARATH A0A1P8AVV1_ARATH A0A1P8AVS9_ARATH function Nuclease required for the repair of DNA interstrand cross-links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions.
FAN1_ARATH-3 FAN1_ARATH FAN1_ARATH-2 function Nuclease required for the repair of DNA interstrand cross-links (ICLs) (PubMed:25779053). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions (By similarity). May act upstream of the helicase RECQL4A and the ATPase RAD5A, which is involved in error-free post-replicative repair. Functions independently of MUS81 pathway, but in a similar pathway with RECQ4A, RAD5A and MFH1 in ICL repair (PubMed:25779053).
FAN1_ARATH-3 A0A1P8AVS5_ARATH FAN1_ARATH FAN1_ARATH-2 A0A1P8AVV1_ARATH A0A1P8AVS9_ARATH similarity Belongs to the FAN1 family.
FAN1_ARATH-3 FAN1_ARATH FAN1_ARATH-2 subcellular location Localizes to stalled replication forks via its UBZ-type zinc finger.

6 Proteins

Function

Interactions

Interaction Network

Show the following interaction types:
Reset view
Show in table format
Export graph

Click on a gene to get more info about it.

Expression

eFP Visualization

Data Source: BAR




Co-expression

Querying ATTED Service...
Data Source: ATTED-II
Top N
LS: LS is a monotonic transformation (negative logit) of MR index. Larger LS indicates stronger co-expression.

 

Homology

Phytozome Homologs

Data Source: Phytozome


0 Homologues

 

Other

7 Data Sets