DB identifier
|
AT1G48050 | Secondary Identifier
|
locus:2023757 |
| Brief Description | Ku80 family protein |
| TAIR Computational Description | Ku80 family protein;(source:Araport11) |
| TAIR Curator Summary | Ku80 and ku70 form the heterodimer complex Ku, required for proper maintenance of the telomeric C strand. Ku regulates the extension of the telomeric G strand. Interacts with WEX, and this interaction stimulates the WEX exonuclease activity. Binds double stranded DNA breaks as a heterodimer with Ku70, involved in non-homologous end joining repair. Mutants are defective in T-DNA integration. Over expression confers increased resistance to DNA damage agents and increased susceptibility to T-DNA transformation. |
| TAIR Short Description | Ku80 family protein |
| TAIR Aliases | ATKU80, KU80 |
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