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Gene : VPS46.1 A. thaliana

DB identifier  ? AT1G17730 Secondary Identifier  ? locus:2007883
Name  ? vacuolar protein sorting 46.1 Brief Description  vacuolar protein sorting 46.1
TAIR Computational Description  vacuolar protein sorting 46.1;(source:Araport11)
TAIR Curator Summary  Encodes an ESCRT-related protein: CHMP1A/AT1G73030; CHMP1B/AT1G17730. CHMP1A and B mediate multivesicular body sorting of auxin carriers and are required for plant development. ESCRT: Endosomal Sorting Complexes Required For Transport machinery; CHMP: Charged Multivesicular Body Protein/Chromatin Modifying Protein.
TAIR Short Description  vacuolar protein sorting 46.1
TAIR Aliases  CHMP1B, VPS46.1

2 Gene Rifs

1 Organism

12 Publications

0 Synonyms

Genomics

Genome feature

Region: gene ? Length: 1359  
Location: Chr1:6099039-6100397

Gene models - VPS46.1 AT1G17730

? Gene models

Transcripts: 1  Exons: 2  Introns: 1 

Overlapping Features

? Genome features that overlap coordinates of this Gene

3 Child Features

1 Cross References

1 Downstream Intergenic Region

0 Located Features

1 Upstream Intergenic Region

Proteins

Curated comments from UniProt

Type Comment Proteins
CHM1A_ARATH function Involved in ESCRT-dependent multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Mediates the MVB sorting of the auxin carriers PIN1, PIN2 and AUX1. Required for embryonic axis establishment and seedling growth (PubMed:19304934). Required for autophagic degradation of plastid proteins. Promotes the efficient sequestration of cargo from plastids into autophagosomes. Mediates the efficient delivery of autophagic plastid bodies to the vacuole, but not into the cytoplasm (PubMed:25649438).
CHM1A_ARATH similarity Belongs to the SNF7 family.

1 Proteins

Function

Gene Ontology

cellular component
nucleus  ? ECO  
endosome membrane  ? ECO  
molecular function
No terms in this category.
biological process
embryonic axis specification  ? ECO  
endosome transport via multivesicular body sorting pathway  ? ECO  
protein transport  ? ECO  
vacuolar transport  ? ECO  
autophagy  ? ECO  
seedling development  ? ECO  
embryo development ending in seed dormancy  ? ECO  

Interactions

Interaction Network

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Expression

eFP Visualization

Data Source: BAR




Co-expression

Querying ATTED Service...
Data Source: ATTED-II
Top N
LS: LS is a monotonic transformation (negative logit) of MR index. Larger LS indicates stronger co-expression.

 

Homology

Phytozome Homologs

Data Source: Phytozome


0 Homologues

 

Other

9 Data Sets