cytochrome c biogenesis protein family;(source:Araport11)
TAIR Curator Summary
Encodes a protein with oxidoreductase activity present in the inner membrane of mitochondria. CCMH is postulated to play a central role in mitochondrial cytochrome c maturation, probably as part of a heme lyase complex that also holds activity of reducing apocytochrome c. CCMH interacts with apocytochrome AtCYTc-a and is shown to be present in a 500 kDa-complex along with CcmFN2.
Encodes SHH1, a homeodomain protein required for DNA methylation. It is an atypical RNA-directed DNA methylation component, and functions in transcriptional silencing through both DNA methylation-dependent and -independent pathways.
Plays a central role in mitochondrial cytochrome c maturation. Probable component of a heme lyase complex involved in the reduction of apocytochrome c (PubMed:16236729). Forms a complex with CCMF proteins (CCMFC, CCMFN1 and CCMFN2) that performs the assembly of heme with c-type apocytochromes in mitochondria (PubMed:18644794).