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Gene : AT1G12400 A. thaliana

DB identifier  ? AT1G12400 Secondary Identifier  ? locus:2034685
Brief Description  Nucleotide excision repair, TFIIH, subunit TTDA
TAIR Computational Description  Nucleotide excision repair, TFIIH, subunit TTDA;(source:Araport11)
TAIR Curator Summary  NULL
TAIR Short Description  Nucleotide excision repair, TFIIH, subunit TTDA

0 Gene Rifs

1 Organism

5 Publications

0 Synonyms

Genomics

Genome feature

Region: gene ? Length: 1097  
Location: Chr1:4221779-4222875

Gene models - AT1G12400 AT1G12400

? Gene models

Transcripts: 3  Exons: 8  Introns: 5 

Overlapping Features

? Genome features that overlap coordinates of this Gene

9 Child Features

0 Cross References

1 Downstream Intergenic Region

0 Located Features

0 Upstream Intergenic Region

Proteins

Curated comments from UniProt

Type Comment Proteins
TFB5_ARATH function Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape. Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module CAK controls the initiation of transcription.
A0A1P8AR18_ARATH function In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape.
TFB5_ARATH A0A1P8AR18_ARATH similarity Belongs to the TFB5 family.

2 Proteins

Function

Gene Ontology

cellular component
transcription factor TFIIH holo complex  ? ECO  
transcription factor TFIIH core complex  ? ECO  
molecular function
No terms in this category.
biological process
transcription by RNA polymerase II  ? ECO  
nucleotide-excision repair, preincision complex assembly  ? ECO  
transcription initiation at RNA polymerase II promoter  ? ECO  

Interactions

Interaction Network

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Expression

eFP Visualization

Data Source: BAR




Co-expression

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Data Source: ATTED-II
Top N
LS: LS is a monotonic transformation (negative logit) of MR index. Larger LS indicates stronger co-expression.

 

Homology

Phytozome Homologs

Data Source: Phytozome


0 Homologues

 

Other

5 Data Sets