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Gene : ATX2 A. thaliana

DB identifier  ? AT1G05830 Secondary Identifier  ? locus:2198743
Name  ? trithorax-like protein 2 Brief Description  trithorax-like protein 2
TAIR Computational Description  trithorax-like protein 2;(source:Araport11)
TAIR Curator Summary  Encodes a homolog of trithorax, a histone-lysine N-methyltransferase. Paralog of ATX1. Unlike ATX1 which is involved in trimethylating of histone H3-mysine 4, ATX2 is involved in dimethylating of histone H3-lysine 4. ATX1 and ATX2 influence the expression of largely nonoverlapping gene sets. The expression pattern of ATX2 is also different from that of ATX1.
TAIR Short Description  trithorax-like protein 2
TAIR Aliases  ATX2, SDG30

0 Gene Rifs

1 Organism

15 Publications

0 Synonyms

Genomics

Genome feature

Region: gene ? Length: 7780  
Location: Chr1:1754130-1761909

Gene models - ATX2 AT1G05830

? Gene models

Transcripts: 4  Exons: 101  Introns: 97 

Overlapping Features

? Genome features that overlap coordinates of this Gene

36 Child Features

0 Cross References

1 Downstream Intergenic Region

0 Located Features

1 Upstream Intergenic Region

Proteins

Curated comments from UniProt

Type Comment Proteins
ATX2_ARATH developmental stage Accumulates in adult plants, especially in rosette leaves and roots (but not in the vasculature and in tips) (PubMed:18375658). Weakly expressed in inflorescence nodes and at the base of the flowers (PubMed:18375658). In flowers, present in pollen and, at low levels, at the tips of the stigma (PubMed:18375658). In seedlings, observed in the vasculature and in the shoot apical meristems (PubMed:18375656).
ATX2_ARATH function Histone methyltransferase (PubMed:18375658). Dimethylates 'Lys-4' of histone H3 (H3K4me2) (PubMed:18375658, PubMed:24102415). H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation (PubMed:18375658). Methylates only a limited fraction of nucleosomes of target genes (e.g. NAP and XTH33) (PubMed:18375658). Involved in epigenetic regulation of the floral repressor FLC and FT to prevent the transition from vegetative to reproductive development (PubMed:18375656, PubMed:24102415).
ATX2_ARATH similarity Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. TRX/MLL subfamily.
ATX2_ARATH tissue specificity Expressed in roots, leaves and flowers and, to a lower extent, in young seedlings.

1 Proteins

Function

Interactions

Interaction Network

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Expression

eFP Visualization

Data Source: BAR




Co-expression

Querying ATTED Service...
Data Source: ATTED-II
Top N
LS: LS is a monotonic transformation (negative logit) of MR index. Larger LS indicates stronger co-expression.

 

Homology

Phytozome Homologs

Data Source: Phytozome


0 Homologues

 

Other

6 Data Sets