Genomics
Genome feature
| Region: |
gene
|
Length: |
3497
 |
| Location: | Chr1:262828-266324 | ||
Overlapping Features
Genome features that overlap coordinates of this Gene
Proteins
Curated comments from UniProt
| Type | Comment | Proteins |
|---|---|---|
| ACH2_ARATH | function | Catalyzes the hydrolysis of acyl-CoAs into free fatty acids and coenzyme A (CoASH), regulating their respective intracellular levels (PubMed:11171266, PubMed:14660652). Active with both medium chain and long chain acyl-CoAs (e.g. 12:0-CoA, 14:0-CoA, 16:0-CoA, 18:0-CoA, 16:1-CoA, 18:1-CoA, 18:2-CoA and 20:4-CoA) as substrates, palmitoleoyl-CoA (16:1-CoA) being the favorite substrate (PubMed:11171266, PubMed:14660652). |
| ACH2_ARATH | pathway | Lipid metabolism; fatty acid metabolism. |
| ACH2_ARATH | similarity | Belongs to the C/M/P thioester hydrolase family. |
| ACH2_ARATH | subcellular location | Predominantly localized in the peroxisome but a localization to the cytosol cannot be excluded. |
| ACH2_ARATH | tissue specificity | Mostly expressed in leaves and flowers, and, to a lower extent, in seedlings and siliques. |
Function
Gene Ontology
| cellular component | |
|---|---|
|
peroxisome
|
ECO |
|
peroxisomal matrix
|
ECO |
| molecular function | |
|
medium-chain fatty acyl-CoA hydrolase activity
|
ECO |
|
long-chain fatty acyl-CoA hydrolase activity
|
ECO |
|
fatty acyl-CoA hydrolase activity
|
ECO |
| biological process | |
|
protein homotetramerization
|
ECO |
|
acyl-CoA metabolic process
|
ECO |
|
fatty acid metabolic process
|
ECO |
Interactions
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