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Search results 1 to 100 out of 128761 for Genome-wide association study

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Publication
First Author: Mattheisen M
Title: Genome-wide association study in obsessive-compulsive disorder: results from the OCGAS.
Year: 2015
Journal: Mol Psychiatry
Volume: 20
Pages: 337-44
Publication
First Author: Otowa T
Title: Genome-wide association study of panic disorder in the Japanese population.
Year: 2009
Journal: J Hum Genet
Volume: 54
Pages: 122-6
Publication
First Author: Atwell S
Title: Genome-wide association study of 107 phenotypes in Arabidopsis thaliana inbred lines.
Year: 2010
Journal: Nature
Volume: 465
Pages: 627-31
Publication
First Author: Barber MJ
Title: Genome-wide association of lipid-lowering response to statins in combined study populations.
Year: 2010
Journal: PLoS One
Volume: 5
Pages: e9763
Publication
First Author: Zuo L
Title: Genome-wide association study of alcohol dependence implicates KIAA0040 on chromosome 1q.
Year: 2012
Journal: Neuropsychopharmacology
Volume: 37
Pages: 557-66
Publication
First Author: Proietti S
Title: Genome-wide association study reveals novel players in defense hormone crosstalk in Arabidopsis.
Year: 2018
Journal: Plant Cell Environ
Volume: 41
Pages: 2342-2356
Publication
First Author: Di Bernardo MC
Title: A genome-wide association study identifies six susceptibility loci for chronic lymphocytic leukemia.
Year: 2008
Journal: Nat Genet
Volume: 40
Pages: 1204-10
Publication
First Author: Filiault DL
Title: A genome-wide association study identifies variants underlying the Arabidopsis thaliana shade avoidance response.
Year: 2012
Journal: PLoS Genet
Volume: 8
Pages: e1002589
Publication
First Author: Wang LE
Title: Genome-wide association study reveals novel genetic determinants of DNA repair capacity in lung cancer.
Year: 2013
Journal: Cancer Res
Volume: 73
Pages: 256-64
Publication
First Author: Meijón M
Title: Genome-wide association study using cellular traits identifies a new regulator of root development in Arabidopsis.
Year: 2014
Journal: Nat Genet
Volume: 46
Pages: 77-81
Publication
First Author: Rhodes DH
Title: Genome-wide association study of grain polyphenol concentrations in global sorghum [Sorghum bicolor (L.) Moench] germplasm.
Year: 2014
Journal: J Agric Food Chem
Volume: 62
Pages: 10916-27
Gene
Length: 892  
Chromosome Location: Chr2: 18846944-18847835
Organism . Short Name: A. thaliana
TAIR Computational Description: BON association protein 2;(source:Araport11)
TAIR Curator Summary: encodes a protein that is similar to BONZAI1-binding protein BAP1.
TAIR Short Description: BON association protein 2
TAIR Aliases: BAL, BAP2
Gene
Length: 1478  
Chromosome Location: Chr3: 22650159-22651636
Organism . Short Name: A. thaliana
TAIR Computational Description: BON association protein 1;(source:Araport11)
TAIR Curator Summary: Encodes a protein with a C2 domain that binds to BON1 in yeast two hybrid analyses. Its ability to bind to phospholipids is enhanced by calcium ions. Involved in maintaining cell homeostasis.
TAIR Short Description: BON association protein 1
TAIR Aliases: BAP1
Publication
First Author: Genetic Analysis of Psoriasis Consortium & the Wellcome Trust Case Control Consortium 2.
Title: A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1.
Year: 2010
Journal: Nat Genet
Volume: 42
Pages: 985-90
Publication
First Author: Yuan J
Title: A genome-wide association study reveals a novel regulator of ovule number and fertility in Arabidopsis thaliana.
Year: 2019
Journal: PLoS Genet
Volume: 15
Pages: e1007934
Publication
First Author: van Heel DA
Title: A genome-wide association study for celiac disease identifies risk variants in the region harboring IL2 and IL21.
Year: 2007
Journal: Nat Genet
Volume: 39
Pages: 827-9
Publication
First Author: Gretarsdottir S
Title: Genome-wide association study identifies a sequence variant within the DAB2IP gene conferring susceptibility to abdominal aortic aneurysm.
Year: 2010
Journal: Nat Genet
Volume: 42
Pages: 692-7
Publication
First Author: Raudsepp T
Title: Genome-wide association study implicates testis-sperm specific FKBP6 as a susceptibility locus for impaired acrosome reaction in stallions.
Year: 2012
Journal: PLoS Genet
Volume: 8
Pages: e1003139
Publication
First Author: Li F
Title: Genome-wide association study dissects the genetic architecture of seed weight and seed quality in rapeseed (Brassica napus L.).
Year: 2014
Journal: DNA Res
Volume: 21
Pages: 355-67
Publication
First Author: Sadhukhan A
Title: Genome-wide Association Study Reveals that the Aquaporin NIP1;1 Contributes to Variation in Hydrogen Peroxide Sensitivity in Arabidopsis thaliana.
Year: 2017
Journal: Mol Plant
Volume: 10
Pages: 1082-1094
Protein Domain
Gene
Length: 3318  
Chromosome Location: Chr3: 19188844-19192161
Organism . Short Name: A. thaliana
TAIR Computational Description: inflorescence meristem receptor-like kinase 2;(source:Araport11)
TAIR Curator Summary: encodes a leucine-repeat receptor kinase expressed in inflorescence meristem. Locus association was made from performing sequence analysis with IMK3 (MRLK) whose locus association was provided by the authors. The mRNA is cell-to-cell mobile.
TAIR Short Description: inflorescence meristem receptor-like kinase 2
TAIR Aliases: IMK2
Publication
First Author: Branham SE
Title: Genome-Wide Association Study in Arabidopsis thaliana of Natural Variation in Seed Oil Melting Point: A Widespread Adaptive Trait in Plants.
Year: 2016
Journal: J Hered
Volume: 107
Pages: 257-65
Protein Domain
Gene
Length: 2956  
Chromosome Location: Chr4: 16102595-16105550
Organism . Short Name: A. thaliana
TAIR Computational Description: histone deacetylase 14;(source:Araport11)
TAIR Curator Summary: Encodes HDA14, a member of the histone deacetylase family proteins that can deacetylate a-tubulin, associates with a/b-tubulin and is retained on GTP/taxol-stabilized microtubules, at least in part, by direct association with the PP2A-A2 subunit. The association of a histone deacetylase with PP2A suggests a direct link between protein phosphorylation and acetylation.
TAIR Short Description: histone deacetylase 14
TAIR Aliases: ATHDA14, AtHDAC14, HDA14, HDAC14
Gene
Length: 1756  
Chromosome Location: Chr2: 6642300-6644055
Organism . Short Name: A. thaliana
TAIR Computational Description: translocon at inner membrane of chloroplasts 21;(source:Araport11)
TAIR Curator Summary: Encodes a protein located in the chloroplast inner envelope. The study of mutant defective in the gene product suggests that the protein is involved in the translocation of protein across the envelope membrane into the chloroplast stroma.
TAIR Short Description: translocon at inner membrane of chloroplasts 21
TAIR Aliases: AtTic21, CIA5, PIC1, TIC21
Gene
Length: 3132  
Chromosome Location: Chr1: 9500892-9504023
Organism . Short Name: A. thaliana
TAIR Computational Description: squamosa promoter-like 11;(source:Araport11)
TAIR Curator Summary: In conjunction with SPL10 and SPL2, SPL11 redundantly controls proper development of lateral organs in association with shoot maturation in the reproductive phase.
TAIR Short Description: squamosa promoter-like 11
TAIR Aliases: SPL11
Publication
First Author: Hong MG
Title: Genome-wide and gene-based association implicates FRMD6 in Alzheimer disease.
Year: 2012
Journal: Hum Mutat
Volume: 33
Pages: 521-9
Gene
Length: 3378  
Chromosome Location: Chr3: 3267825-3271202
Organism . Short Name: A. thaliana
TAIR Computational Description: NAC domain containing protein 52;(source:Araport11)
TAIR Curator Summary: Encodes a NAC transcription factor that physically associates with the histone H3K4 demethylase JMJ14 and through that association is involved in transcriptional repression and flowering time control.
TAIR Short Description: NAC domain containing protein 52
TAIR Aliases: ANAC051, ANAC052, NAC052, SGS1
Protein Domain
Gene
Length: 3431  
Chromosome Location: Chr1: 9505112-9508542
Organism . Short Name: A. thaliana
TAIR Computational Description: squamosa promoter binding protein-like 10;(source:Araport11)
TAIR Curator Summary: In conjunction with SPL11 and SPL2, SPL10 redundantly controls proper development of lateral organs in association with shoot maturation in the reproductive phase. SPL10 also controls lamina shape during vegetative development.
TAIR Short Description: squamosa promoter binding protein-like 10
TAIR Aliases: SPL10
Gene
Length: 4143  
Chromosome Location: Chr5: 9243398-9247540
Organism . Short Name: A. thaliana
TAIR Computational Description: Major facilitator superfamily protein;(source:Araport11)
TAIR Curator Summary: Encodes a protein with high affinity, hexose-specific/H+ symporter activity. The activity of the transporter appears to be negatively regulated by phosphorylation. Importantly, microarray analysis, as well as the study of the expression of this gene in mutants involved in programmed cell death (PCD) demonstrated a tight correlation between this gene's expression and PCD.
TAIR Short Description: Major facilitator superfamily protein
TAIR Aliases: ATSTP13, MSS1, STP13
Gene
Length: 2493  
Chromosome Location: Chr5: 2600443-2602935
Organism . Short Name: A. thaliana
TAIR Computational Description: movement protein binding protein 2C;(source:Araport11)
TAIR Curator Summary: Microtubule-associated and viral movement protein binding protein. Negatively regulates KN1 association to plasmodesmata and, consequently, cell-to-cell transport. Involved in the alignment of cortical microtubules, the patterning of stomata and in restricting tobamoviral infections.
TAIR Short Description: movement protein binding protein 2C
TAIR Aliases: MPB2C
Gene
Length: 2884  
Chromosome Location: Chr2: 11063301-11066184
Organism . Short Name: A. thaliana
TAIR Computational Description: alpha-vacuolar processing enzyme;(source:Araport11)
TAIR Curator Summary: Encodes a vacuolar processing enzyme belonging to a novel group of cysteine proteinases that is expressed in vegetative organs and is upregulated in association with various types of cell death and under stressed conditions.
TAIR Short Description: alpha-vacuolar processing enzyme
TAIR Aliases: AEP1, ALPHA-VPE, ALPHAVPE
Gene
Length: 5242  
Chromosome Location: Chr5: 1444638-1449879
Organism . Short Name: A. thaliana
TAIR Computational Description: aminophospholipid ATPase 1;(source:Araport11)
TAIR Curator Summary: Encodes a putative aminophospholipid translocase (p-type ATPase) involved in chilling response. It is targeted to the plasma membrane following association in the endoplasmic reticulum with an ALIS protein beta-subunit. The mRNA is cell-to-cell mobile.
TAIR Short Description: aminophospholipid ATPase 1
TAIR Aliases: ALA1
Publication
First Author: Wang K
Title: Diverse genome-wide association studies associate the IL12/IL23 pathway with Crohn Disease.
Year: 2009
Journal: Am J Hum Genet
Volume: 84
Pages: 399-405
Publication
First Author: Li H
Title: Candidate single-nucleotide polymorphisms from a genomewide association study of Alzheimer disease.
Year: 2008
Journal: Arch Neurol
Volume: 65
Pages: 45-53
Gene
Length: 3502  
Chromosome Location: Chr3: 3264194-3267695
Organism . Short Name: A. thaliana
TAIR Computational Description: NAC domain containing protein 50;(source:Araport11)
TAIR Curator Summary: Encodes a NAC transcription factor that physically associates with the histone H3K4 demethylase JMJ14 and through that association is involved in transcriptional repression and flowering time control. It binds the NAC-binding site, the Mitochondrial Dysfunction Motif.
TAIR Short Description: NAC domain containing protein 50
TAIR Aliases: ANAC050, NAC050, NAC50
Gene
Length: 8912  
Chromosome Location: Chr3: 19332828-19341739
Organism . Short Name: A. thaliana
TAIR Computational Description: tetratricopeptide repeat (TPR)-containing protein;(source:Araport11)
TAIR Curator Summary: Involved in regulating mitochondrial quality control. Regulates mitochondrial association time and thereby is involved in mitochondrial fusion. Mutants show unregulated autophagy and display transcriptomic markers of mitochondrial stress. Its activity can be modulated by Lys acetylation.
TAIR Short Description: tetratricopeptide repeat (TPR)-containing protein
TAIR Aliases: FMT, FRIENDLY, NOXY38
Gene  
Length: 4461  
Chromosome Location: Chr4: 15248377-15252837
Organism . Short Name: A. thaliana
TAIR Computational Description: flocculation protein;(source:Araport11)
TAIR Curator Summary: Encodes a plant-specific protein that physically interacts with CRWN1 and its homolog CRWN4 and localizes at the inner nuclear membrane. KAKU4 deforms the nuclear envelope in a dose-dependent manner, in association with nuclear membrane invagination and stack formation.
TAIR Aliases: KAKU4
Publication
First Author: Danik JS
Title: Novel loci, including those related to Crohn disease, psoriasis, and inflammation, identified in a genome-wide association study of fibrinogen in 17 686 women: the Women's Genome Health Study.
Year: 2009
Journal: Circ Cardiovasc Genet
Volume: 2
Pages: 134-41
Gene
Length: 3232  
Chromosome Location: Chr1: 25908046-25911277
Organism . Short Name: A. thaliana
TAIR Computational Description: WPP domain-interacting protein 2;(source:Araport11)
TAIR Curator Summary: Encodes one of the WPP domain-interacting proteins (WIT1/AT5G11390, WIT2/AT1G68910) required for RanGAP nuclear envelope association in root tip cells. Ran GTPase plays essential roles in multiple cellular processes, including nucleocytoplasmic transport, spindle formation, and postmitotic nuclear envelope reassembly. The cytoplasmic Ran GTPase activating protein RanGAP is critical to establish a functional RanGTP/RanGDP gradient across the nuclear envelope and is associated with the outer surface of the nuclear envelope in metazoan and higher plant cells. Arabidopsis thaliana RanGAP association with the root tip nuclear envelope requires a family of likely plant-specific nucleoporins combining coiled-coil and transmembrane domains (CC-TMD) and WPP domain-interacting proteins (WIPs). WIT1 and WIT2 have been identified as a second family of CC-TMD proteins, structurally similar, yet clearly distinct from the WIP family, that is required for RanGAP nuclear envelop association in root tip cells.
TAIR Short Description: WPP domain-interacting protein 2
TAIR Aliases: WIT2
Gene
Length: 3286  
Chromosome Location: Chr5: 3633649-3636934
Organism . Short Name: A. thaliana
TAIR Computational Description: WPP domain-interacting protein 1;(source:Araport11)
TAIR Curator Summary: Encodes one of the WPP domain-interacting proteins (WIT1/AT5G11390, WIT2/AT1G68910) required for RanGAP nuclear envelope association in root tip cells. Ran GTPase plays essential roles in multiple cellular processes, including nucleocytoplasmic transport, spindle formation, and postmitotic nuclear envelope reassembly. The cytoplasmic Ran GTPase activating protein RanGAP is critical to establish a functional RanGTP/RanGDP gradient across the nuclear envelope and is associated with the outer surface of the nuclear envelope in metazoan and higher plant cells. Arabidopsis thaliana RanGAP association with the root tip nuclear envelope requires a family of likely plant-specific nucleoporins combining coiled-coil and transmembrane domains (CC-TMD) and WPP domain-interacting proteins (WIPs). WIT1 and WIT2 have been identified as a second family of CC-TMD proteins, structurally similar, yet clearly distinct from the WIP family, that is required for RanGAP nuclear envelop association in root tip cells.
TAIR Short Description: WPP domain-interacting protein 1
TAIR Aliases: WIT1
Publication
First Author: Pihlstrøm L
Title: Supportive evidence for 11 loci from genome-wide association studies in Parkinson's disease.
Year: 2013
Journal: Neurobiol Aging
Volume: 34
Pages: 1708.e7-13
Publication
First Author: Núñez JG
Title: Study of AtSUS2 localization in seeds reveals a strong association with plastids.
Year: 2008
Journal: Plant Cell Physiol
Volume: 49
Pages: 1621-6
Publication
First Author: Santiago JL
Title: Study of the association between the CAPSL-IL7R locus and type 1 diabetes.
Year: 2008
Journal: Diabetologia
Volume: 51
Pages: 1653-8
Publication
First Author: Ohshige T
Title: Association of new loci identified in European genome-wide association studies with susceptibility to type 2 diabetes in the Japanese.
Year: 2011
Journal: PLoS One
Volume: 6
Pages: e26911
Gene
Length: 1084  
Chromosome Location: Chr4: 8418242-8419325
Organism . Short Name: A. thaliana
TAIR Computational Description: Chlorophyll A-B binding family protein;(source:Araport11)
TAIR Curator Summary: Encodes an early light-induced protein. ELIPs are thought not to be directly involved in the synthesis and assembly of specific photosynthetic complexes, but rather affect the biogenesis of all chlorophyll-binding complexes. A study (PMID 17553115) has shown that the chlorophyll synthesis pathway was downregulated as a result of constitutive ELIP2 expression, leading to decreased chlorophyll availability for the assembly of pigment-binding proteins for photosynthesis.
TAIR Short Description: Chlorophyll A-B binding family protein
TAIR Aliases: ELIP2
Gene
Length: 3594  
Chromosome Location: Chr5: 17360287-17363880
Organism . Short Name: A. thaliana
TAIR Computational Description: squamosa promoter binding protein-like 2;(source:Araport11)
TAIR Curator Summary: member of the SPL (squamosa-promoter binding protein-like) gene family, a novel gene family encoding DNA binding proteins and putative transcription factors. In conjunction with SPL10 and SPL11, SPL2 redundantly controls proper development of lateral organs in association with shoot maturation in the reproductive phase.
TAIR Short Description: squamosa promoter binding protein-like 2
TAIR Aliases: SPL2
Interaction Term
Interaction Term
Ontology Term Synonym
Name: functional association
Type: synonym
Ontology Term Synonym
Name: molecular association
Type: synonym
Publication
First Author: Chan EK
Title: Understanding the evolution of defense metabolites in Arabidopsis thaliana using genome-wide association mapping.
Year: 2010
Journal: Genetics
Volume: 185
Pages: 991-1007
Gene
Length: 3923  
Chromosome Location: Chr3: 3331064-3334986
Organism . Short Name: A. thaliana
TAIR Computational Description: calmodulin-domain protein kinase cdpk isoform 2;(source:Araport11)
TAIR Curator Summary: predicted to encode calcium-dependent protein kinase and is localized to the ER. Protein is myristoylated in a cell-free extract. Changing the proposed myristoylated site, G residue in the amino terminal, to A prevented the meristoylation . The G to A mutation decreased AtCPK2 membrane association by approximately 50%.
TAIR Short Description: calmodulin-domain protein kinase cdpk isoform 2
TAIR Aliases: ATCPK2, CPK2
GeneRIF (Gene Reference into Function)
Annotation: Genome-wide chromatin association of NRPE1 is dependent on all members of a putative chromatin-remodeling complex termed DDR, which includes the proteins DRD1, DMS3 and RDM1.
Organism: A. thaliana
Gene: DRD1
PubMed Id: 22864289
GeneRIF (Gene Reference into Function)
Annotation: Genome-wide chromatin association of NRPE1 is dependent on all members of a putative chromatin-remodeling complex termed DDR, which includes the proteins DRD1, DMS3 and RDM1.
Organism: A. thaliana
Gene: NRPD1B
PubMed Id: 22864289
GeneRIF (Gene Reference into Function)
Annotation: Genome-wide chromatin association of NRPE1 is dependent on all members of a putative chromatin-remodeling complex termed DDR, which includes the proteins DRD1, DMS3 and RDM1.
Organism: A. thaliana
Gene: RDM1
PubMed Id: 22864289
GeneRIF (Gene Reference into Function)
Annotation: Genome-wide chromatin association of NRPE1 is dependent on all members of a putative chromatin-remodeling complex termed DDR, which includes the proteins DRD1, DMS3 and RDM1.
Organism: A. thaliana
Gene: DMS3
PubMed Id: 22864289
Gene
Length: 2803  
Chromosome Location: Chr3: 21196517-21199319
Organism . Short Name: A. thaliana
TAIR Computational Description: eukaryotic translation initiation factor 3E;(source:Araport11)
TAIR Curator Summary: Encodes a protein that is found in not only the eif3 complex but also in association with subunits of the COP9 signalosome. eIF3e appears to be subjected to proteasome-dependent degradation that requires the PCI domain of eIF3e. The level of eIF3e present in cells appears to affect the rate of translation.
TAIR Short Description: eukaryotic translation initiation factor 3E
TAIR Aliases: ATEIF3E-1, ATINT6, EIF3E, INT-6, INT6, TIF3E1
Gene
Length: 3254  
Chromosome Location: Chr4: 15900270-15903523
Organism . Short Name: A. thaliana
TAIR Computational Description: gamma vacuolar processing enzyme;(source:Araport11)
TAIR Curator Summary: Encodes a vacuolar processing enzyme belonging to a novel group of cysteine proteinases that is expressed in vegetative organs and is upregulated in association with various types of cell death and under stressed conditions. They are essential in processing seed storage proteins and for mediating the susceptible response of toxin-induced cell death.
TAIR Short Description: gamma vacuolar processing enzyme
TAIR Aliases: AEP3, AtLEG gamma, GAMMA-VPE, GAMMAVPE, LEG gamma
Publication
First Author: Psychiatric GWAS Consortium Bipolar Disorder Working Group.
Title: Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4.
Year: 2011
Journal: Nat Genet
Volume: 43
Pages: 977-83
Gene
Length: 3097  
Chromosome Location: Chr2: 9051725-9054821
Organism . Short Name: A. thaliana
TAIR Computational Description: magnesium transporter, putative (DUF803);(source:Araport11)
TAIR Curator Summary: Encodes a putative magnesium transporter that was identified through a forward genetic screen, directly isolating antiviral RNAi-defective (avi) mutant using a Cucumber Mosaic Virus (CMV) mutant. Compared to Wildtype Col-0, avi2 mutant showed severe disease symptom after viral infection and viral accumulation was significantly increased while viral siRNAs and virus-activated endogenous siRNAs (vasiRNAs) were reduced in avi2 mutant. Detailed genetic study indicated that AVI2 modulated RNAi-mediated antiviral immunity by regulating the biogenesis of secondary viral siRNAs and vasiRNAs in Arabidopsis.
TAIR Short Description: Protein of unknown function (DUF803)
TAIR Aliases: AVI2, ENOR3
Protein Domain
Gene
Length: 9937  
Chromosome Location: Chr1: 2723677-2733613
Organism . Short Name: A. thaliana
TAIR Computational Description: P-loop containing nucleoside triphosphate hydrolases superfamily protein;(source:Araport11)
TAIR Curator Summary: The Arabidopsis ATRX harbours a N-terminal ADD domain and a C-terminal helicase domain and is devoid of the large central region involved in DAXX interaction in mammals. Arabidopsis ATRX mutant alleles are viable, but with reduced fertility. Their combination with mutants for the H3.3 chaperone HIRA impairs plant survival. ATRX loss affects cellular histone H3.3 pools and modulates the H3.1/H3.3 balance. Notably, at a genome-wide scale, loss of ATRX leads to a reduced H3.3 level at genes characterized by elevated H3.3 occupancy and high expression, including the 45S ribosomal DNA (45S rDNA) loci. Indeed, expression of specific 45S rDNA sequence variants is altered by ATRX loss (DOI:10.1105/tpc.16.00877)
TAIR Short Description: P-loop containing nucleoside triphosphate hydrolases superfamily protein
TAIR Aliases: ATRX, CHR20
Publication
First Author: Rajarammohan S
Title: Genome-wide association mapping in Arabidopsis identifies novel genes underlying quantitative disease resistance to Alternaria brassicae.
Year: 2018
Journal: Mol Plant Pathol
Volume: 19
Pages: 1719-1732
Publication
First Author: Duggan D
Title: Two genome-wide association studies of aggressive prostate cancer implicate putative prostate tumor suppressor gene DAB2IP.
Year: 2007
Journal: J Natl Cancer Inst
Volume: 99
Pages: 1836-44
Publication
First Author: Ren D
Title: A new regulator of seed size control in Arabidopsis identified by a genome-wide association study.
Year: 2019
Journal: New Phytol
Volume: 222
Pages: 895-906
Publication
First Author: Milne RL
Title: 7q21-rs6964587 and breast cancer risk: an extended case-control study by the Breast Cancer Association Consortium.
Year: 2011
Journal: J Med Genet
Volume: 48
Pages: 698-702
Gene
Length: 5229  
Chromosome Location: Chr5: 20715453-20720681
Organism . Short Name: A. thaliana
TAIR Computational Description: CLPC homologue 1;(source:Araport11)
TAIR Curator Summary: Encodes a protein that is similar to ATP-dependent Clp protease ATP-binding subunit / ClpC. Involved in protein import into the chloroplast. May provide ATP source that drives the TIC (Translocon at the Inner envelope membrane of Chloroplasts) translocation machinery. Association of Hsp93 with the inner envelope membrane through its N domain is important for the functions of Hsp93 in vivo.
TAIR Short Description: CLPC homologue 1
TAIR Aliases: ATHSP93-V, CLPC, CLPC1, DCA1, HSP93-V
Ontology Term Synonym
Name: matrix association region
Type: synonym
Ontology Term Synonym
Name: nascent polypeptide association
Type: synonym
Ontology Term Synonym
Name: protein self association
Type: synonym
Gene
Length: 1998  
Chromosome Location: Chr5: 5392576-5394573
Organism . Short Name: A. thaliana
TAIR Computational Description: Alpha-1,4-glucan-protein synthase family protein;(source:Araport11)
TAIR Curator Summary: RGP5 is a member of the reversably-glycosylated family of proteins. Analyses using tagged RGP5 suggest that it is present in the cytosol and in association with the Golgi apparatus. Recombinant RGP5 does not have UDP-arabinose mutase activity based on an in vitro assay even though the related RGP1, RGP2, and RGP3 proteins do have activity in the same assay. RGP5 can form complexes with RGP1 and RGP2.
TAIR Short Description: Alpha-1,4-glucan-protein synthase family protein
TAIR Aliases: RGP5
Publication
First Author: Chao DY
Title: Genome-wide association mapping identifies a new arsenate reductase enzyme critical for limiting arsenic accumulation in plants.
Year: 2014
Journal: PLoS Biol
Volume: 12
Pages: e1002009
Publication
First Author: Broekgaarden C
Title: Novel Genes Affecting the Interaction between the Cabbage Whitefly and Arabidopsis Uncovered by Genome-Wide Association Mapping.
Year: 2015
Journal: PLoS One
Volume: 10
Pages: e0145124
Gene
Length: 4522  
Chromosome Location: Chr4: 16086311-16090832
Organism . Short Name: A. thaliana
TAIR Computational Description: BRI1-associated receptor kinase;(source:Araport11)
TAIR Curator Summary: Leu-rich receptor Serine/threonine protein kinase. Component of BR signaling that interacts with BRI1 in vitro and in vivo to form a heterodimer. Brassinolide-dependent association of BRI1 and BAK1 in vivo. Phosphorylation of both BRI1 and BAK1 on Thr residues was BR dependent. Although BAK1 and BRI1 alone localize in the plasma membrane, when BAK1 and BRI1 are coexpressed, the heterodimer BAK1/BRI1 they form is localized in the endosome.
TAIR Short Description: BRI1-associated receptor kinase
TAIR Aliases: ATBAK1, ATSERK3, BAK1, ELG, RKS10, SERK3
Gene
Length: 1796  
Chromosome Location: Chr5: 20640992-20642787
Organism . Short Name: A. thaliana
TAIR Computational Description: reversibly glycosylated polypeptide 4;(source:Araport11)
TAIR Curator Summary: RGP4 is a reversibly glycosylated polypeptide. Analyses using tagged RGP4 suggest that it is present in the cytosol and in association with the Golgi apparatus. Recombinant RGP4 does not have UDP-arabinose mutase activity based on an in vitro assay even though the related RGP1, RGP2, and RGP3 proteins do have activity in the same assay. RGP4 can form complexes with RGP1 and RGP2. RGP4 is expressed during seed development.
TAIR Short Description: reversibly glycosylated polypeptide 4
TAIR Aliases: RGP4
Publication
First Author: Heim MA
Title: The basic helix-loop-helix transcription factor family in plants: a genome-wide study of protein structure and functional diversity.
Year: 2003
Journal: Mol Biol Evol
Volume: 20
Pages: 735-47
GeneRIF (Gene Reference into Function)
Annotation: Using genome-wide association studies, the authors first identified allelic variation of the Lyso-PhosphatidylCholine (PC) AcylTransferase 1 (LPCAT1) gene as the key determinant of shoot inorganic phosphate accumulation under zinc deficiency.
Organism: A. thaliana
Gene: LPLAT1
PubMed Id: 29453864
Publication
First Author: Marino C
Title: A family-based association study does not support DYX1C1 on 15q21.3 as a candidate gene in developmental dyslexia.
Year: 2005
Journal: Eur J Hum Genet
Volume: 13
Pages: 491-9
Gene
Length: 8257  
Chromosome Location: Chr2: 14795715-14803971
Organism . Short Name: A. thaliana
TAIR Computational Description: transcription activator;(source:Araport11)
TAIR Curator Summary: Component of the WAVE protein complex which act as activators of ARP2/3 complex involved in actin nucleation. Required for trichome morphogenesis. Mutant displays distorted trichomes, a phenotype that can be phenocopied by treatment of WT plants with actin-interacting drugs. Its ER localization is independent of upstream SPK1 activation signaling and the physical association with the WAVE/SCAR Regulatory complex binding partner SRA1. ER-localized NAP1 has little colocalization with actin and represent the inactive pool of NAP1 in these cell types.
TAIR Short Description: transcription activators
TAIR Aliases: GRL, LPL3, NAP1, NAPP
Protein Domain
Ontology Term Synonym
Name: nuclear matrix association region
Type: synonym
Ontology Term Synonym
Name: cohesin association with chromatin
Type: synonym
Publication
First Author: Chen C
Title: PICARA, an analytical pipeline providing probabilistic inference about a priori candidates genes underlying genome-wide association QTL in plants.
Year: 2012
Journal: PLoS One
Volume: 7
Pages: e46596
Publication
First Author: Verslues PE
Title: Genome-wide association mapping combined with reverse genetics identifies new effectors of low water potential-induced proline accumulation in Arabidopsis.
Year: 2014
Journal: Plant Physiol
Volume: 164
Pages: 144-59
Protein Domain
Publication
First Author: Rathcke CN
Title: Association of polymorphisms of the CHI3L1 gene with asthma and atopy: a populations-based study of 6514 Danish adults.
Year: 2009
Journal: PLoS One
Volume: 4
Pages: e6106
GO Term
Description: A form of mutualism between a fungus and the roots of a vascular plant, where hyphae of the fungus penetrate the plant cell wall and invaginate its cell membrane. Once inside, the fungus forms highly branched structures for nutrient exchange with the plant called arbuscules. Aids in the acquisition by the plant of nutrients such as phosphorus from the soil.
Publication
First Author: Hou S
Title: Replication study confirms the association between UBAC2 and Behçet's disease in two independent Chinese sets of patients and controls.
Year: 2012
Journal: Arthritis Res Ther
Volume: 14
Pages: R70
Publication
First Author: Hollis-Moffatt JE
Title: Only one independent genetic association with rheumatoid arthritis within the KIAA1109-TENR-IL2-IL21 locus in Caucasian sample sets: confirmation of association of rs6822844 with rheumatoid arthritis at a genome-wide level of significance.
Year: 2010
Journal: Arthritis Res Ther
Volume: 12
Pages: R116
Publication
First Author: Chao DY
Title: Genome-wide association studies identify heavy metal ATPase3 as the primary determinant of natural variation in leaf cadmium in Arabidopsis thaliana.
Year: 2012
Journal: PLoS Genet
Volume: 8
Pages: e1002923
Publication
First Author: Hao GP
Title: Nucleotide variation in the NCED3 region of Arabidopsis thaliana and its association study with abscisic acid content under drought stress.
Year: 2009
Journal: J Integr Plant Biol
Volume: 51
Pages: 175-83
GeneRIF (Gene Reference into Function)
Annotation: Genome-wide association mapping identified PHOSPHATE 1 (PHO1) and genes such as Root System Architecture 1 (RSA1) associated with differences in root allometry, a highly plastic trait capturing the distribution of lateral roots along the primary axis.
Organism: A. thaliana
Gene: PHO1
PubMed Id: 23980140
Ontology Term Synonym
Name: regulation of nascent polypeptide association
Type: synonym
Gene
Length: 3525  
Chromosome Location: Chr1: 3837694-3841218
Organism . Short Name: A. thaliana
TAIR Computational Description: partner of Y14-MAGO;(source:Araport11)
TAIR Curator Summary: The PYM gene encodes a protein capable of interacting with MAGO, and Y14, whose orthologs form part of the exon junction complex in animal cells. In vitro binding assays indicate that PYM can bind to MAGO and Y14 either individually, or when they are together. But, MAGO-Y14-PYM ternary complexes are difficult to detect in vivo in Arabidopsis based on pull-down experiments. However there is some evidence for a weak association in Arabidopsis flowers. PYM appears primarily cytoplasmic, but it also seems to into the nucleus at times. Its nuclear localization signal has not been rigorously defined, but there is evidence for a nuclear export signal between amino acids 171-205 in the C-terminus.
TAIR Short Description: partner of Y14-MAGO
TAIR Aliases: PYM
Publication
First Author: Guan F
Title: Two-stage association study to identify the genetic susceptibility of a novel common variant of rs2075290 in ZPR1 to type 2 diabetes.
Year: 2016
Journal: Sci Rep
Volume: 6
Pages: 29586
Publication
First Author: Brachi B
Title: Genome-wide association mapping of flowering time in Arabidopsis thaliana in nature: genetics for underlying components and reaction norms across two successive years.
Year: 2013
Journal: Acta Bot Gallica
Volume: 160
Pages: 205-219
Ontology Term Synonym
Name: regulation of cohesin association with chromatin
Type: synonym