help  | faq  | software  | BAR

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, pathways, authors, ontology terms, etc. (e.g. eve, embryo, zen, allele)
  • Use OR to search for either of two terms (e.g. fly OR drosophila) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. dros* for partial matches or fly AND NOT embryo to exclude a term

Search results 701 to 800 out of 3178 for reactive oxygen species

0.058s

Categories

Hits by Category

Hits by Organism

Type Details Score
Protein Domain
GeneRIF (Gene Reference into Function)
Annotation: By influencing the levels of reactive oxygen species, AtOXR2 improves the efficiency of photosynthesis and elicits basal tolerance to environmental challenges that increase oxidative stress, allowing improved plant growth and biomass production.
Organism: A. thaliana
Gene: AT2G05590
PubMed Id: 30945737
Protein Domain
Protein Domain
Protein Domain
Protein Domain
Protein Domain
Protein Domain
Protein Domain
Gene
Length: 3891  
Chromosome Location: Chr1: 23808835-23812725
Organism . Short Name: A. thaliana
TAIR Computational Description: Uncharacterized protein family (UPF0016);(source:Araport11)
TAIR Curator Summary: Encodes an integral thylakoid membrane protein that is required for normal operation of oxygen-evolving complex (as evidenced by oxygen evolution rates) and for manganese incorporation. PAM71 belongs to a small gene family in Arabidopsis comprising five members. PAM71 is well conserved in the green lineage and shares homology with putative Ca2+/H+ exchangers from yeast (Saccharomyces cerevisiae) (GDT1) and human (Homo sapiens) (TMEM165).
TAIR Short Description: Uncharacterized protein family (UPF0016)
TAIR Aliases: BICAT1, CCHA1, PAM71
Gene
Length: 1773  
Chromosome Location: Chr5: 25526509-25528281
Organism . Short Name: A. thaliana
TAIR Computational Description: NAC domain containing protein 102;(source:Araport11)
TAIR Curator Summary: Encodes a member of the NAC family of transcription factors. ANAC102 appears to have a role in mediating response to low oxygen stress (hypoxia) in germinating seedlings. Its expression can be induced by beta-cyclocitral, an oxidized by-product of beta-carotene generated in the chloroplasts, mediates a protective retrograde response that lowers the levels of toxic peroxides and carbonyls, limiting damage to intracellular components.
TAIR Short Description: NAC domain containing protein 102
TAIR Aliases: ANAC102, NAC102
Publication
First Author: Jin S
Title: Expression of γ-tocopherol methyltransferase in chloroplasts results in massive proliferation of the inner envelope membrane and decreases susceptibility to salt and metal-induced oxidative stresses by reducing reactive oxygen species.
Year: 2014
Journal: Plant Biotechnol J
Volume: 12
Pages: 1274-85
Ontology Term
Description: Protein involved in hypersensitive response, a complex and early defense response that causes necrosis and cell death to restrict the growth of a pathogen. Local and systemic biochemical changes include generation of active oxygen species (oxidative burst), cell death, overproduction of lignin-related materials, and the induction of certain proteins such as pathogen related (PR) proteins
GO Term
Description: The directed movement of oxygen (O2) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO Term
Description: Binding to oxygen (O2).
Protein Domain
GO Term
Description: The series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced in response to oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, and ends when the execution phase of apoptosis is triggered.
GO Term
Description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
GO Term
Description: Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
GO Term
Description: The series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a neuron. The pathway is induced in response to oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, and ends when the execution phase of apoptosis is triggered.
GO Term
Description: Any process that decreases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
Protein Domain
Gene
Length: 1722  
Chromosome Location: Chr1: 8398115-8399836
Organism . Short Name: A. thaliana
TAIR Computational Description: Oxidoreductase, zinc-binding dehydrogenase family protein;(source:Araport11)
TAIR Curator Summary: AOR is an alkenal/one oxidoreductase that acts on compounds with unsaturated alpha,beta-carbonyls. The activity of this enzyme with a number of substrates, including acrolein and 3-buten-2-one, was demonstrated in vitro using a truncated form of the protein that lacked approximately 80 of the first amino acids. This protein appears to localize to the chloroplast where it likely helps to maintain the photosynthetic process by detoxifying reactive carbonyls formed during lipid peroxidation.
TAIR Short Description: Oxidoreductase, zinc-binding dehydrogenase family protein
TAIR Aliases: AOR
Gene
Length: 1837  
Chromosome Location: Chr1: 1703002-1704838
Organism . Short Name: A. thaliana
TAIR Computational Description: Uridine diphosphate glycosyltransferase 74E2;(source:Araport11)
TAIR Curator Summary: Encodes a UDP-glucosyltransferase, UGT74E2, that acts on IBA (indole-3-butyric acid) and affects auxin homeostasis. The transcript and protein levels of this enzyme are strongly induced by H2O2 and may allow integration of ROS (reactive oxygen species) and auxin signaling. This enzyme can also transfer glycosyl groups to several compounds related to the explosive TNT when this synthetic compound is taken up from the environment.
TAIR Short Description: Uridine diphosphate glycosyltransferase 74E2
TAIR Aliases: UGT74E2
Publication
First Author: Kimura S
Title: Protein phosphorylation is a prerequisite for the Ca2+-dependent activation of Arabidopsis NADPH oxidases and may function as a trigger for the positive feedback regulation of Ca2+ and reactive oxygen species.
Year: 2012
Journal: Biochim Biophys Acta
Volume: 1823
Pages: 398-405
Protein Domain
Gene
Length: 2427  
Chromosome Location: Chr2: 18297878-18300304
Organism . Short Name: A. thaliana
TAIR Computational Description: repressor of lrx1;(source:Araport11)
TAIR Curator Summary: Encodes ROL5, a repressor of lrx1 mutants that develop aberrant root hairs. ROL5 is a homolog of yeast Ncs6p that affects TOR signaling. The target of rapamycin (TOR) pathway is a major regulator of cell growth in eukaryotes, and inhibition of this pathway by rapamycin reduces cell growth. ROL5 might function as a mitochondrial component of the TOR pathway that influences the plant's response to ROS (reactive oxygen species).
TAIR Short Description: repressor of lrx1
TAIR Aliases: ROL5
GO Term
Description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
Protein Domain
Protein Domain
Gene
Length: 1645  
Chromosome Location: Chr3: 22662849-22664493
Organism . Short Name: A. thaliana
TAIR Computational Description: NAD(P)-binding Rossmann-fold superfamily protein;(source:Araport11)
TAIR Curator Summary: CytADR/SDR1 is an aldehyde reductase that catalyzes the reduction of the aldehyde carbonyl groups on alpha,beta-unsaturated aldehydes with more than 5 carbons in vitro. It can also act on menthone and neomenthol in vitro, but these do not represent likely endogenous activities of this enzyme in planta. GFP-tagged CytADR appears to localize to the cytosol where it likely plays a role in detoxifying reactive carbonyls. sdr1 mutants have altered responses to pathogens. The mRNA is cell-to-cell mobile.
TAIR Short Description: NAD(P)-binding Rossmann-fold superfamily protein
TAIR Aliases: SDR1
GO Term
Description: Any process that modulates the frequency, rate or extent of oxygen metabolic process.
Gene
Length: 1696  
Chromosome Location: Chr1: 20458952-20460647
Organism . Short Name: A. thaliana
TAIR Computational Description: NAD(P)-binding Rossmann-fold superfamily protein;(source:Araport11)
TAIR Curator Summary: ChlADR is an aldehyde reductase that catalyzes the reduction of the aldehyde carbonyl groups on saturated and alpha,beta-unsaturated aldehydes with more than 5 carbons in vitro. The N-terminal region of this protein directs GFP to the chloroplast where where ChlADR likely helps to maintain the photosynthetic process by detoxifying reactive carbonyls formed during lipid peroxidation. In addition, this enzyme can also reduce cis-3-hexenal, a major plant volatile compound that contributes to green leaf odor, as well as methylglyoxal in vitro.
TAIR Short Description: NAD(P)-binding Rossmann-fold superfamily protein
TAIR Aliases: ChlADR
Protein Domain
GO Term
Description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of oxygen.
Ontology Term Synonym
Name: oxygen free radical metabolism
Type: synonym
Ontology Term Synonym
Name: iron(II): oxygen oxidoreductase activity
Type: synonym
Ontology Term Synonym
Name: (gibberrellin-20),2-oxoglutarate: oxygen oxidoreductase (3beta-hydroxylating)
Type: synonym
Ontology Term Synonym
Name: regulation of oxygen metabolism
Type: synonym
Ontology Term Synonym
Name: diatomic oxygen metabolic process
Type: synonym
Ontology Term Synonym
Name: cellular response to oxygen
Type: synonym
Protein Domain
Protein Domain
Publication
First Author: Spyrakis F
Title: Oxygen binding to Arabidopsis thaliana AHb2 nonsymbiotic hemoglobin: evidence for a role in oxygen transport.
Year: 2011
Journal: IUBMB Life
Volume: 63
Pages: 355-62
Protein Domain
Gene
Length: 1435  
Chromosome Location: Chr3: 1035238-1036672
Organism . Short Name: A. thaliana
TAIR Computational Description: NAD(P)-binding Rossmann-fold superfamily protein;(source:Araport11)
TAIR Curator Summary: ChlADR is an aldehyde reductase that catalyzes the reduction of the aldehyde carbonyl groups on saturated and alpha,beta-unsaturated aldehydes with more than 5 carbons in vitro. The N-terminal region of this protein directs GFP to the chloroplast where where ChlADR likely helps to maintain the photosynthetic process by detoxifying reactive carbonyls formed during lipid peroxidation. In addition, this enzyme can also reduce cis-3-hexenal, a major plant volatile compound that contributes to green leaf odor, as well as methylglyoxal in vitro. Involved in higher growth rates under elevated CO2 conditions.
TAIR Short Description: NAD(P)-binding Rossmann-fold superfamily protein
TAIR Aliases: ChlADR
Protein Domain
Protein Domain
Protein Domain
Protein Domain
Interaction Experiment
Name: Schmidt HB (2015)
Description: Nup98 FG domains from diverse species spontaneously phase-separate into particles with nuclear pore-like permselectivity.
Publication
First Author: Poole RK
Title: Reactions of the Escherichia coli flavohaemoglobin (Hmp) with oxygen and reduced nicotinamide adenine dinucleotide: evidence for oxygen switching of flavin oxidoreduction and a mechanism for oxygen sensing.
Year: 1994
Journal: Proc Biol Sci
Volume: 255
Pages: 251-8
Gene
Length: 2048  
Chromosome Location: Chr5: 23683784-23685831
Organism . Short Name: A. thaliana
TAIR Computational Description: Pmr5/Cas1p GDSL/SGNH-like acyl-esterase family protein (DUF828);(source:Araport11)
TAIR Curator Summary: Belongs to a large family of plant-specific genes of unknown function. Involved in resistance to the powdery mildew species Erysiphe cichoracearum and Erysiphe orontii, but not to the unrelated pathogens Pseudomonas syringae or Peronospora parasitica. A member of the TBL (TRICHOME BIREFRINGENCE-LIKE) gene family containing a plant-specific DUF231 (domain of unknown function) domain. TBL gene family has 46 members, two of which (TBR/AT5G06700 and TBL3/AT5G01360) have been shown to be involved in the synthesis and deposition of secondary wall cellulose, presumably by influencing the esterification state of pectic polymers. A nomenclature for this gene family has been proposed (Volker Bischoff & Wolf Scheible, 2010, personal communication).
TAIR Short Description: Plant protein of unknown function (DUF828)
TAIR Aliases: PMR5, TBL44
Publication
First Author: Bailey-Serres J
Title: Making sense of low oxygen sensing.
Year: 2012
Journal: Trends Plant Sci
Volume: 17
Pages: 129-38
Publication
First Author: Flors C
Title: Imaging the production of singlet oxygen in vivo using a new fluorescent sensor, Singlet Oxygen Sensor Green.
Year: 2006
Journal: J Exp Bot
Volume: 57
Pages: 1725-34
Ontology Term
Description: Enzymes that reduce molecular oxygen by incorporating one oxygen atom into its substrate and the other one in water
Protein Domain
GO Term
Description: Any process that stops, prevents or reduces the frequency, rate or extent of oxygen metabolic process.
GO Term
Description: Any process that activates or increases the frequency, rate or extent of oxygen metabolic process.
GO Term
Description: Catalysis of the incorporation of one atom from molecular oxygen into a compound and the reduction of the other atom of oxygen to water.
GO Term
Description: Catalysis of the incorporation of one atom from molecular oxygen into arachidonic acid and the reduction of the other atom of oxygen to water.
Publication
First Author: Bailey CJ
Title: The reactive serine residue of epidermolytic toxin A.
Year: 1990
Journal: Biochem J
Volume: 269
Pages: 535-7
GO Term
Description: The series of events in which an oxygen stimulus is received by a cell and converted into a molecular signal.
GO Term
Description: Binding to oxygen and delivering it to an acceptor molecule or a specific location.
GO Term
Description: Catalysis of the reaction: 2 H2O = O2 + 4 H+ + 4 e-. The evolution of oxygen from oxidizing water is carried out by the oxygen evolving complex in photosystem II of plants. P680+, the photochemically oxidized reaction-center chlorophyll of PSII, is a strong biological oxidant. The reduction potential of P680+ is more positive than that of water, and thus it can oxidize water to give O2 and H+ ions. The oxygen escapes as a gas while the H+ ions remain in solution inside the thylakoid vesicle.
GO Term
Description: Binding to and responding, e.g. by conformational change, to changes in the cellular level of oxygen (O2).
Protein Domain
Protein Domain
GO Term
Description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxygen-containing compound stimulus.
GO Term
Description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting a decline in the level of oxygen.
GO Term
Description: The series of events in which a stimulus indicating lowered oxygen tension is received by a cell and converted into a molecular signal. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.
GO Term
Description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting an increase in the level of oxygen.
Ontology Term Synonym
Name: oxygen free radical metabolic process
Type: synonym
Ontology Term Synonym
Name: positive regulation of oxygen metabolism
Type: synonym
Ontology Term Synonym
Name: negative regulation of oxygen metabolism
Type: synonym
Ontology Term Synonym
Name: response to lowered oxygen tension
Type: synonym
Ontology Term Synonym
Name: detection of reduced oxygen levels
Type: synonym
Ontology Term Synonym
Name: response to oxygen molecular entity
Type: synonym
Ontology Term Synonym
Name: removal of oxygen free radicals
Type: synonym
Ontology Term Synonym
Name: peptidyl-lysine, 2-oxoglutarate: oxygen oxidoreductase activity
Type: synonym
Ontology Term Synonym
Name: response to increased oxygen tension
Type: synonym
Ontology Term Synonym
Name: response to raised oxygen levels
Type: synonym
Ontology Term Synonym
Name: response to lowered oxygen levels
Type: synonym
Protein Domain
Protein Domain
Publication
First Author: Kiger L
Title: Trematode hemoglobins show exceptionally high oxygen affinity.
Year: 1998
Journal: Biophys J
Volume: 75
Pages: 990-8
Gene
Length: 5248  
Chromosome Location: Chr2: 16598072-16603319
Organism . Short Name: A. thaliana
TAIR Computational Description: delta1-pyrroline-5-carboxylate synthase 1;(source:Araport11)
TAIR Curator Summary: encodes a delta1-pyrroline-5-carboxylate synthase that catalyzes the rate-limiting enzyme in the biosynthesis of proline. Gene is expressed in reproductive organs and tissues under non-stress conditions but in the whole plant under water-limiting condition. Expression is also induced by abscisic acid and salt stress in a light-dependent manner. encodes a delta1-pyrroline-5-carboxylate synthase that catalyzes the rate-limiting enzyme in the biosynthesis of proline. Gene is expressed in reproductive organs and tissues under non-stress conditions but in the whole plant under water-limiting condition. Expression is also induced by abscisic acid and salt stress in a light-dependent manner. P5CS1 appears to be involved in salt stress responses related to proline accumulation, including protection from reactive oxidative species. P5CS1 appears to be present in different cells and/or different subcellular locations from P5CS2 in a tissue-dependent manner.
TAIR Short Description: delta1-pyrroline-5-carboxylate synthase 1
TAIR Aliases: ATP5CS, P5CS1
Protein Domain
Publication
First Author: McBride JD
Title: Peptide mimics of the Bowman-Birk inhibitor reactive site loop.
Year: 2002
Journal: Biopolymers
Volume: 66
Pages: 79-92
Publication
First Author: Guo CJ
Title: Discovery of Reactive Microbiota-Derived Metabolites that Inhibit Host Proteases.
Year: 2017
Journal: Cell
Volume: 168
Pages: 517-526.e18
Protein Domain
Ontology Term
Description: Protein involved in the transport of oxygen (e.g. hemoglobin and myoglobin)
UniProt Feature
Begin: 227
Description: Abolishes cyanide-resistant oxygen consumption.
Type: mutagenesis site
End: 227
UniProt Feature
Begin: 296
Description: Abolishes cyanide-resistant oxygen consumption.
Type: mutagenesis site
End: 296
UniProt Feature
Begin: 299
Description: Abolishes cyanide-resistant oxygen consumption.
Type: mutagenesis site
End: 299
UniProt Feature
Begin: 136
Description: Abolishes cyanide-resistant oxygen consumption.
Type: mutagenesis site
End: 136
UniProt Feature
Begin: 178
Description: Abolishes cyanide-resistant oxygen consumption.
Type: mutagenesis site
End: 178
UniProt Feature
Begin: 175
Description: Abolishes cyanide-resistant oxygen consumption.
Type: mutagenesis site
End: 175
Protein Domain
Protein Domain