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Search results 43001 to 43100 out of 43842 for cell

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Type Details Score
Protein Domain
IPR037219
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Protein Domain
IPR037270
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Protein Domain
IPR037268
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Protein Domain
IPR037140
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Protein Domain
IPR037139
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Protein Domain
IPR003960
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Protein Domain
IPR003996
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Protein Domain
IPR001370
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Protein Domain
IPR008054
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Protein Domain
IPR011029
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Protein Domain
IPR001562
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Protein Domain
IPR023257
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Protein Domain
IPR001743
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Protein Domain
IPR033544
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Protein Domain
IPR025723
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Protein Domain
IPR037742
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Protein Domain
IPR011124
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Protein Domain
IPR023336
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Protein Domain
IPR011641
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Protein Domain
IPR057246
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Protein Domain
IPR057247
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Protein Domain
IPR011723
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Protein Domain
IPR008121
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Protein Domain
IPR021160
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Protein Domain
IPR057440
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Protein Domain
IPR057397
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Protein Domain
IPR008752
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Protein Domain
IPR006241
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Protein Domain
IPR006343
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Protein Domain
IPR008984
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Protein Domain
IPR006182
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Protein Domain
IPR006217
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UniProt Feature
UniProt Feature
Begin: 825
Description: Impaired interaction with RKS1 and reduced ability to mediate cell death as well as an increased sensitivity to the pathogenic biotrophic bacteria Xanthomonas campestris pv. campestris (Xcc); when associated with A-839.
Type: mutagenesis site
End: 825
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UniProt Feature
UniProt Feature
Begin: 839
Description: Impaired interaction with RKS1 and reduced ability to mediate cell death as well as an increased sensitivity to the pathogenic biotrophic bacteria Xanthomonas campestris pv. campestris (Xcc); when associated with A-825.
Type: mutagenesis site
End: 839
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UniProt Feature
UniProt Feature
Begin: 339
Description: In pmr6-5; strong powdery mildew resistance, cell walls of plants are enriched for pectins with a lower degree of esterification and an alteration in the H bonding environment of cellulose microfibrils.
Type: mutagenesis site
End: 339
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UniProt Feature
UniProt Feature
Begin: 140
Description: In pmr6-1; strong powdery mildew resistance, cell walls of plants are enriched for pectins with a lower degree of esterification and an alteration in the H bonding environment of cellulose microfibrils.
Type: mutagenesis site
End: 140
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Ontology Term
- | Viral ion channel
Description: Small transmembrane protein that homo-oligomerizes to form a viral ion channel usually expressed in the viral envelope and host cell membranes. These channels affect membrane permeability to ions and play an important role in facilitating virus entry, assembly and release, as well as modulating the ion homeostasis of host cells Viral ion channels are not necessarily required for the production of infectious virions, although their expression usually significantly increases growth. During influenza A virus entry for example, the M2 proton channel allows protons from the acidic endosome to enter the enveloped virion, initiating pH-dependent uncoating of the genome. In certain influenza A subtypes, M2 also equilibrates the intraluminal pH of the trans-Golgi network with the cytoplasm, preventing premature conformational changes in the viral fusion protein during budding
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Protein Domain
IPR020775
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Protein Domain
IPR003268
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Protein Domain
IPR003271
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Protein Domain
IPR002284
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Protein Domain
IPR001571
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Protein Domain
IPR002285
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Protein Domain
IPR002441
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Protein Domain
IPR001771
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Protein Domain
IPR057454
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GO Term
GO:2000734 | negative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation
Description: Any process that stops, prevents or reduces the frequency, rate or extent of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation.
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GO Term
GO:2000735 | positive regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation
Description: Any process that activates or increases the frequency, rate or extent of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation.
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GO Term
GO:1990499 | raps-insc complex
Description: Protein complex required for the asymmetric division of neuroblasts in Drosophila. Coordinates asymmetric localization of cell fate determinants with orientation of the mitotic spindle resulting in different daughter cells upon division. Localizes at the apical cortex of the neuroblast: Raps maintains, but does not initiate, Insc apically, while Insc segregates Raps asymmetrically. Complex appears to be conserved in mammals (composed of INSC and GPSM1 or GPSM2).
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GO Term
GO:0000410 | carbon catabolite repression of transcription by galactose
Description: A transcription regulation process in which the presence of galactose that leads to a decrease in the frequency, rate, or extent of transcription of specific genes involved in the metabolism of other carbon sources. Carbon catabolite repression is a mechanism of genetic regulation which the accumulation of catabolites of one substance in the cell represses the formation of enzymes that contribute to the catabolism of other substances.
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GO Term
GO:0045014 | carbon catabolite repression of transcription by glucose
Description: A transcription regulation process in which the presence of glucose leads to a decrease in the frequency, rate, or extent of transcription of specific genes involved in the metabolism of other carbon sources. Carbon catabolite repression is a mechanism of genetic regulation which the accumulation of catabolites of one substance in the cell represses the formation of enzymes that contribute to the catabolism of other substances.
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GO Term
GO:0000708 | meiotic strand invasion
Description: The cell cycle process in which the nucleoprotein complex (composed of the broken single-strand DNA and the recombinase) searches and identifies a region of homology in intact duplex DNA. The broken single-strand DNA displaces the like strand and forms Watson-Crick base pairs with its complement, forming a duplex in which each strand is from one of the two recombining DNA molecules. This occurs during meiosis.
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GO Term
GO:0001101 | response to acid chemical
Description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by the chemical structure of the anion portion of a dissociated acid (rather than the acid acting as a proton donor). The acid chemical may be in gaseous, liquid or solid form.
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GO Term
GO:0009608 | response to symbiont
Description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a symbiont, an organism living with an organism of a different species in close physical association. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.
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GO Term
GO:0042092 | type 2 immune response
Description: An immune response which is associated with resistance to extracellular organisms such as helminths and pathological conditions such as allergy, which is orchestrated by the production of particular cytokines, most notably IL-4, IL-5, IL-10, and IL-13, by any of a variety of cell types including T-helper 2 cells, eosinophils, basophils, mast cells, and nuocytes, resulting in enhanced production of certain antibody isotypes and other effects.
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GO Term
GO:0005905 | clathrin-coated pit
Description: A part of the endomembrane system in the form of an invagination of a membrane upon which a clathrin coat forms, and that can be converted by vesicle budding into a clathrin-coated vesicle. Coated pits form on the plasma membrane, where they are involved in receptor-mediated selective transport of many proteins and other macromolecules across the cell membrane, in the trans-Golgi network, and on some endosomes.
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GO Term
GO:0080135 | regulation of cellular response to stress
Description: Any process that modulates the frequency, rate or extent of a cellular response to stress. Cellular response to stress is a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
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GO Term
GO:0009953 | dorsal/ventral pattern formation
Description: The regionalization process in which the areas along the dorsal/ventral axis are established that will lead to differences in cell differentiation. The dorsal/ventral axis is defined by a line that runs orthogonal to both the anterior/posterior and left/right axes. The dorsal end is defined by the upper or back side of an organism. The ventral end is defined by the lower or front side of an organism.
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GO Term
GO:0010165 | response to X-ray
Description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of X-ray radiation. An X-ray is a form of electromagnetic radiation with a wavelength in the range of 10 nanometers to 100 picometers (corresponding to frequencies in the range 30 PHz to 3 EHz).
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GO Term
GO:0010583 | response to cyclopentenone
Description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cyclopentenone stimulus. Cyclopentenones are oxylipins derived from polyunsaturated fatty acids. They are structurally similar to jasmonic acid, but contain a reactive unsaturated carbonyl structure in the cyclo-ring. Cyclopentenones include phytoprostanes and 12-oxo-phytodienoic acid.
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GO Term
GO:0014072 | response to isoquinoline alkaloid
Description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an isoquinoline alkaloid stimulus. An isoquinoline alkaloid is any member of a group of compounds with the heterocyclic ring structure of benzo(c)pyridine which is a structure characteristic of the group of opium alkaloids.
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GO Term
GO:0021514 | ventral spinal cord interneuron differentiation
Description: The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of ventral spinal cord interneurons. Ventral spinal cord interneurons are cells located in the ventral portion of the spinal cord that transmit signals between sensory and motor neurons and are required for reflexive responses. Differentiation includes the processes involved in commitment of a cell to a specific fate.
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GO Term
GO:0021526 | medial motor column neuron differentiation
Description: The process in which differentiating motor neurons in the neural tube acquire the specialized structural and/or functional features of medial motor column neurons. Medial motor column neurons are generated at all rostrocaudal levels and send axons to the axial muscles (medial group) and to the body wall muscles (lateral group). Differentiation includes the processes involved in commitment of a cell to a specific fate.
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GO Term
GO:0031389 | Rad17 RFC-like complex
Description: A pentameric protein complex related to replication factor C, which loads a trimeric complex of checkpoint proteins (known as the checkpoint clamp or 9-1-1 complex) onto DNA at damage sites; functions in DNA damage cell cycle checkpoints. In Schizosaccharomyces pombe the subunits are known as Rad17, Rfc2, Rfc3, Rfc4, and Rfc5, while in Saccharomyces cerevisiae the subunits are known as Rad24p, Rfc2p, Rfc3p, Rfc4p, and Rfc5p.
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GO Term
GO:0035151 | regulation of tube size, open tracheal system
Description: Ensuring that an epithelial tube in an open tracheal system is of the correct length and diameter. Tracheal tubes undergo highly regulated tube-size increases during development, expanding up to 40 times their initial size by the end of larval life. Tube size appears to be controlled by regulation of apical membrane expansion and secretion, rather than by changes in cell number, size or shape.
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GO Term
GO:0051384 | response to glucocorticoid
Description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucocorticoid stimulus. Glucocorticoids are hormonal C21 corticosteroids synthesized from cholesterol with the ability to bind with the cortisol receptor and trigger similar effects. Glucocorticoids act primarily on carbohydrate and protein metabolism, and have anti-inflammatory effects.
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GO Term
GO:0051409 | response to nitrosative stress
Description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrosative stress stimulus. Nitrosative stress is a state often resulting from exposure to high levels of nitric oxide (NO) or the highly reactive oxidant peroxynitrite, which is produced following interaction of NO with superoxide anions.
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GO Term
GO:0070268 | cornification
Description: A type of programmed cell death that occurs in the epidermis, morphologically and biochemically distinct from apoptosis. It leads to the formation of corneocytes, i.e. dead keratinocytes containing an amalgam of specific proteins (e.g., keratin, loricrin, SPR and involucrin) and lipids (e.g., fatty acids and ceramides), which are necessary for the function of the cornified skin layer (mechanical resistance, elasticity, water repellence and structural stability).
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GO Term
GO:0071385 | cellular response to glucocorticoid stimulus
Description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucocorticoid stimulus. Glucocorticoids are hormonal C21 corticosteroids synthesized from cholesterol with the ability to bind with the cortisol receptor and trigger similar effects. Glucocorticoids act primarily on carbohydrate and protein metabolism, and have anti-inflammatory effects.
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GO Term
GO:0071464 | cellular response to hydrostatic pressure
Description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrostatic pressure stimulus. Hydrostatic pressure is the force acting on an object in a system where the fluid is at rest (as opposed to moving). The weight of the fluid above the object creates pressure on it.
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GO Term
GO:0071479 | cellular response to ionizing radiation
Description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ionizing radiation stimulus. Ionizing radiation is radiation with sufficient energy to remove electrons from atoms and may arise from spontaneous decay of unstable isotopes, resulting in alpha and beta particles and gamma rays. Ionizing radiation also includes X-rays.
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GO Term
GO:0071500 | cellular response to nitrosative stress
Description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrosative stress stimulus. Nitrosative stress is a state often resulting from exposure to high levels of nitric oxide (NO) or the highly reactive oxidant peroxynitrite, which is produced following interaction of NO with superoxide anions.
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GO Term
GO:0097210 | response to gonadotropin-releasing hormone
Description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gonadotropin-releasing hormone stimulus. Gonadotropin-releasing hormone (GnRH) is a peptide hormone responsible for the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the anterior pituitary. GnRH is synthesized and released by the hypothalamus.
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GO Term
GO:0097330 | response to 5-fluoro-2'-deoxyuridine
Description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 5-fluoro-2'-deoxyuridine stimulus. 5-fluoro-2'-deoxyuridine is a pyrimidine 2'-deoxyribonucleoside compound having 5-fluorouracil as the nucleobase; it is used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.
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GO Term
GO:0097533 | cellular stress response to acid chemical
Description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in cellular homeostasis caused by the chemical structure of the anion portion of a dissociated acid (rather than the acid acting as a proton donor). The acid chemical may be in gaseous, liquid or solid form.
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GO Term
GO:0097570 | cyst wall
Description: The specialized envelope lying outside the cell membrane of a cyst. A cyst is a resting or dormant stage of a microorganism, usually a bacterium or a protist or rarely an invertebrate animal, that helps the organism to survive in unfavorable environmental conditions. In protists such as protozoan parasites alternating cystic- and non-cystic stages, the cyst wall is usually composed of carbohydrates and proteins.
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GO Term
GO:0110143 | magnetosome
Description: A membrane-bound organelle that envelops particles of magnetic iron minerals in magnetotactic bacteria. Magnetosomes form linear chains that align along the cellular motility axis at midcell and function in bacterial navigation along the Earth's magnetic field. They are formed by invagination of the cell inner membrane; in some species they remain connected to the inner membrane, in others they pinch off to form independent intracellular vesicles.
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GO Term
GO:0051701 | biological process involved in interaction with host
Description: An interaction between two organisms living together in more or less intimate association. The term host is used for the larger (macro) of the two members of a symbiosis; the various forms of symbiosis include parasitism, commensalism and mutualism.
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GO Term
GO:0045648 | positive regulation of erythrocyte differentiation
Description: Any process that activates or increases the frequency, rate or extent of erythrocyte differentiation.
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GO Term
GO:0051935 | glutamate reuptake
Description: The uptake of L-glutamate by neurons or glial cells. This process leads to inactivation and recycling of neurotransmitters.
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GO Term
GO:0070245 | positive regulation of thymocyte apoptotic process
Description: Any process that activates or increases the frequency, rate or extent of thymocyte death by apoptotic process.
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Publication
12845702
First Author: Xiao J
Title: Oligophrenin-1, a Rho GTPase-activating protein (RhoGAP) involved in X-linked mental retardation, is expressed in the enteric nervous system.
Year: 2003
Journal: Anat Rec A Discov Mol Cell Evol Biol
Volume: 273
Pages: 671-6
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UniProt Feature
UniProt Feature
Begin: 297
Description: Reduced oligomerization activity associated with a reduced ability to mediate cell death as well as an increased sensitivity to the pathogenic biotrophic bacteria Xanthomonas campestris pv. campestris (Xcc); when associated with A-149.
Type: mutagenesis site
End: 297
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UniProt Feature
UniProt Feature
Begin: 149
Description: Reduced oligomerization activity associated with a reduced ability to mediate cell death as well as an increased sensitivity to the pathogenic biotrophic bacteria Xanthomonas campestris pv. campestris (Xcc); when associated with A-297.
Type: mutagenesis site
End: 149
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GO Term
GO:0002704 | negative regulation of leukocyte mediated immunity
Description: Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte mediated immunity.
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GO Term
GO:0001911 | negative regulation of leukocyte mediated cytotoxicity
Description: Any process that stops, prevents, or reduces the rate of leukocyte mediated cytotoxicity.
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GO Term
GO:0052150 | symbiont-mediated perturbation of host apoptosis
Description: A process in which a symbiont gene product affects host apoptosis, leading to a change in the frequency, rate or extent of apoptosis in the host cell. The host is defined as the larger of the organisms involved in a symbiotic interaction.
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GO Term
GO:1990662 | S100A9 complex
Description: A protein complex composed of a S100A9 dimer and capable of binding to toll-like receptor 4 (TLR4) and the receptor for advanced glycation end products (RAGE) initiating signal transduction through NF-kappa-B pathways. Transports arachidonic acid between the cytosol and the NADPH oxidase complex at the plasma membrane in neutrophils as part of an inflammatory signal cascade leading to an oxidative burst. Complexes with microtubules to increase cell motility.
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GO Term
GO:0005826 | actomyosin contractile ring
Description: A cytoskeletal structure composed of actin filaments and myosin that forms beneath the plasma membrane of many cells, including animal cells and yeast cells, in a plane perpendicular to the axis of the spindle, i.e. the cell division plane. In animal cells, the contractile ring is located at the cleavage furrow. In budding fungal cells, e.g. mitotic S. cerevisiae cells, the contractile ring forms at the mother-bud neck before mitosis.
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GO Term
GO:0005856 | cytoskeleton
Description: A cellular structure that forms the internal framework of eukaryotic and prokaryotic cells. The cytoskeleton includes intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles.
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GO Term
GO:0000155 | phosphorelay sensor kinase activity
Description: Catalysis of the phosphorylation of a histidine residue in response to detection of an extracellular signal such as a chemical ligand or change in environment, to initiate a change in cell state or activity. The two-component sensor is a histidine kinase that autophosphorylates a histidine residue in its active site. The phosphate is then transferred to an aspartate residue in a downstream response regulator, to trigger a response.
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GO Term
GO:0045013 | carbon catabolite repression of transcription
Description: A transcription regulation process in which the presence of one carbon source leads to a decrease in the frequency, rate, or extent of transcription of specific genes involved in the metabolism of other carbon sources. Carbon catabolite repression is a mechanism of genetic regulation which the accumulation of catabolites of one substance in the cell represses the formation of enzymes that contribute to the catabolism of other substances.
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GO Term
GO:0000433 | carbon catabolite repression of transcription from RNA polymerase II promoter by glucose
Description: A transcription regulation process in which the presence of glucose leads to a decrease in the frequency, rate, or extent of transcription of specific RNA polymerase II-transcribed genes involved in the metabolism of other carbon sources. Carbon catabolite repression is a mechanism of genetic regulation which the accumulation of catabolites of one substance in the cell represses the formation of enzymes that contribute to the catabolism of other substances.
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GO Term
GO:0002412 | antigen transcytosis by M cells in mucosal-associated lymphoid tissue
Description: The process of antigen transcytosis carried out by M cells in the mucosal-associated lymphoid tissue (MALT). Transcytosis is the process of the directed movement of endocytosed material through the cell and its exocytosis from the plasma membrane at the opposite side. M cells are specialized epithelia cells with a microfold structure that are adept at moving antigens from the gut lumen to antigen presenting cells in the MALT.
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GO Term
GO:0005923 | bicellular tight junction
Description: An occluding cell-cell junction that is composed of a branching network of sealing strands that completely encircles the apical end of each cell in an epithelial sheet; the outer leaflets of the two interacting plasma membranes are seen to be tightly apposed where sealing strands are present. Each sealing strand is composed of a long row of transmembrane adhesion proteins embedded in each of the two interacting plasma membranes.
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GO Term
GO:0051304 | chromosome separation
Description: The cell cycle process in which paired chromosomes are detached from each other. Chromosome separation begins with the release of cohesin complexes from chromosomes; in budding yeast, this includes the cleavage of cohesin complexes along the chromosome arms, followed by the separation of the centromeric regions. Chromosome separation also includes formation of chromatid axes mediated by condensins, and ends with the disentangling of inter-sister catenation catalyzed by topoisomerase II (topo II).
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GO Term
GO:0071868 | cellular response to monoamine stimulus
Description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monoamine stimulus. A monoamine is any of a group of molecular messengers that contain one amino group that is connected to an aromatic ring by ethylene group (-CH2-CH2-). Monoamines are derived from the aromatic amino acids phenylalanine, tyrosine, histidine and tryptophan.
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GO Term
GO:0010212 | response to ionizing radiation
Description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ionizing radiation stimulus. Ionizing radiation is radiation with sufficient energy to remove electrons from atoms and may arise from spontaneous decay of unstable isotopes, resulting in alpha and beta particles and gamma rays. Ionizing radiation also includes X-rays.
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GO Term
GO:0010202 | response to low fluence red light stimulus
Description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a low fluence red light stimulus. Red light is electromagnetic radiation of wavelength of 580-700nm. Low fluence red light is defined in this case as short pulses of red light followed by darkness, providing a light level of 0.001-0.1 mmol/m2/sec.
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GO Term
GO:0015627 | type II protein secretion system complex
Description: A large protein complex, containing 12-15 subunits, that spans the cell envelope of Gram-negative bacteria and mediates the movement of proteins into the extracellular environment. The complex includes a component in the cytoplasm, an inner membrane subcomplex that reaches into the periplasmic compartment and a secretion pore in the outer membrane. Proteins using the Type II pathway are transported across the cytoplasmic membrane by the Sec or Tat complex.
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