Proteins
Curated comments from UniProt
Type | Comment | Proteins |
---|---|---|
FBRL3_ARATH | function | S-adenosyl-L-methionine-dependent methyltransferase that has the ability to methylate both RNAs and proteins. Involved in pre-rRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in pre-ribosomal RNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA. Also acts as a protein methyltransferase by mediating methylation of 'Gln-105' of histone H2A (H2AQ105me), a modification that impairs binding of the FACT complex and is specifically present at 35S ribosomal DNA locus (By similarity). |
FBRL3_ARATH | similarity | Belongs to the methyltransferase superfamily. Fibrillarin family. |
FBRL3_ARATH | subcellular location | Fibrillar region of the nucleolus. |
FBRL3_ARATH | tissue specificity | Not detectable by RT-PCR. |
Function
Gene Ontology
cellular component | |
---|---|
nucleolus | ECO |
ribonucleoprotein complex | ECO |
molecular function | |
methyltransferase activity | ECO |
RNA binding | ECO |
biological process | |
rRNA processing | ECO |
methylation | ECO |
Interactions
Interaction Network
Show the following interaction types:
Reset view
Show in table format
Export graph
- Click on a gene to get more info about it.