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Gene : ACD5 A. thaliana

DB identifier  ? AT5G51290 Secondary Identifier  ? locus:2176202
Name  ? ACCELERATED CELL DEATH 5 Brief Description  Diacylglycerol kinase family protein
TAIR Computational Description  Diacylglycerol kinase family protein;(source:Araport11)
TAIR Curator Summary  Encodes a ceramide kinase that plays a role in modulating cell death.
TAIR Short Description  Diacylglycerol kinase family protein
TAIR Aliases  ACD5

4 Gene Rifs

1 Organism

13 Publications

0 Synonyms

Genomics

Genome feature

Region: gene ? Length: 4454  
Location: Chr5:20843923-20848376 reverse strand

Gene models - ACD5 AT5G51290

? Gene models

Transcripts: 2  Exons: 25  Introns: 23 

Overlapping Features

? Genome features that overlap coordinates of this Gene

16 Child Features

0 Cross References

0 Downstream Intergenic Region

0 Located Features

1 Upstream Intergenic Region

Proteins

Curated comments from UniProt

Type Comment Proteins
CERK_ARATH function Catalyzes specifically the phosphorylation of ceramide to form ceramide 1-phosphate. Possesses high activity on ceramide analogs (C6, C8 synthetic ceramides) and lower activity on C6 and C8 dihydroceramides. Has weak activity on natural ceramides (a mixture of ceramides from bovine brain) and the synthetic substrate C2 ceramide. Has very poor activity on diacylglycerol and sphingosine. Ceramide is a critical sphingolipid metabolite that induces programmed cell death (PCD) in plants and ceramide-1-phosphate has a PCD suppressive effect. Thus, ceramide phosphorylation plays a role in the modulation of PCD and CERK activity is crucial for the maintenance of cell viability.

2 Proteins

Function

Gene Ontology

cellular component
No terms in this category.
molecular function
ATP binding  ? ECO  
ceramide kinase activity  ? ECO  
calcium ion binding  ? ECO  
biological process
ceramide metabolic process  ? ECO  
regulation of programmed cell death  ? ECO  
cell death  ? ECO  
phosphorylation  ? ECO  

Interactions

Interaction Network

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Expression

eFP Visualization

Data Source: BAR




Co-expression

Querying ATTED Service...
Data Source: ATTED-II
Top N
LS: LS is a monotonic transformation (negative logit) of MR index. Larger LS indicates stronger co-expression.

 

Homology

Phytozome Homologs

Data Source: Phytozome


0 Homologues

 

Other

7 Data Sets