Proteins
Curated comments from UniProt
Type | Comment | Proteins |
---|---|---|
ELP3_ARATH | function | Catalytic tRNA acetyltransferase subunit of the elongator complex which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine) (PubMed:20398216). In the elongator complex, acts as a tRNA uridine(34) acetyltransferase by mediating formation of carboxymethyluridine in the wobble base at position 34 in tRNAs (By similarity). Promotes organ development by modulating cell division rate (PubMed:20080602). Required for auxin distribution or signaling (PubMed:20080602). Required for meristem cell cycle activation at the time of germination (PubMed:23969312). Mediates the establishment of leaf polarity independently of AS2 and the ta-siRNA-related pathway (PubMed:21700721). Indirectly involved in negatively regulating the expression of genes that participate in UV-B responses, such as DNA repair enzymes and enzymes that participate in sunscreen pigment biosynthesis (PubMed:25907565). |
ELP3_ARATH | pathway | tRNA modification; 5-methoxycarbonylmethyl-2-thiouridine-tRNA biosynthesis. |
ELP3_ARATH | similarity | Belongs to the ELP3 family. |
ELP3_ARATH | subcellular location | Localized in euchromatin during interphase. |
ELP3_ARATH | tissue specificity | Expressed in meristematic tissues of in roots, leaves, seedlings, cotyledons, floral buds and shoot apices (PubMed:15894610, PubMed:20080602, PubMed:23969312). Expressed in the shoot meristem and the emerging leaves immediately after germination (PubMed:23969312). In the root, expressed in the transition zone and the upper meristematic zone (PubMed:23969312). |
Function
Gene Ontology
cellular component | |
---|---|
elongator holoenzyme complex | ECO |
cytosol | ECO |
nucleus | ECO |
euchromatin | ECO |
molecular function | |
4 iron, 4 sulfur cluster binding | ECO |
metal ion binding | ECO |
tRNA binding | ECO |
tRNA uridine(34) acetyltransferase activity | ECO |
biological process | |
DNA-mediated transformation | ECO |
regulation of auxin mediated signaling pathway | ECO |
specification of plant organ axis polarity | ECO |
organ growth | ECO |
regulation of leaf formation | ECO |
cell division | ECO |
tRNA wobble uridine modification | ECO |
auxin-activated signaling pathway | ECO |
Interactions
Interaction Network
Show the following interaction types:
Reset view
Show in table format
Export graph
- Click on a gene to get more info about it.