DB identifier
|
AT5G45307 | Secondary Identifier
|
locus:1009023473 |
| Name
|
microRNA168B |
| TAIR Computational Description | microRNA ath-MIR168b precursor;(source:Araport11) |
| TAIR Curator Summary | Encodes a microRNA that targets AGO1. MicroRNAs are regulatory RNAs with a mature length of ~21-nucleotides that are processed from hairpin precursors by Dicer-like enzymes. MicroRNAs can negatively regulate gene expression by attenuating translation or by directing mRNA cleavage.Mature sequence: UCGCUUGGUGCAGGUCGGGAA. MIR168a is highly expressed and predominantly produces a 21-nt miR168 species. By contrast, MIR168b is expressed at low levels and produces an equal amount of 21- and 22-nt miR168 species. Only the 21-nt miR168 is preferentially stabilized by AGO1, and consequently, the accumulation of the 22-nt but not the 21-nt miR168 is reduced when DCL1 activity is impaired. mir168a mutants with strongly reduced levels of 21-nt miR168 are viable but exhibit developmental defects, particularly during environmentally challenging conditions. |
| TAIR Short Description | MIR168/MIR168B; miRNA |
| TAIR Aliases | MIR168, MIR168B |
Powered by
Have you tried our InterMine mobile apps?
and interoperation is funded by 
