Proteins
Curated comments from UniProt
Type | Comment | Proteins |
---|---|---|
SBT61_ARATH | function | Serine protease that catalyzes the first step (site-1 cleavage) in the proteolytic activation of various factors, prior to site-2 cleavage. Part of a regulated intramembrane proteolysis (RIP) cascade. Cleaves BZIP17 and BZIP28 after the Arg-Arg-Ile-Leu (RRIL) motif. May cleave BZIP49 after the RRIL motif. Targets the membrane-associated BZIP17 factor, which functions as a stress sensor and transducer in a signaling pathway that resembles an ER stress response. Following salt stress, BZIP17 is cleaved by SBT6.1 (S1P) and S2P at the C-terminus and the N-terminal bZIP component is translocated to the nucleus, where it activates the expression of salt stress response genes (PubMed:17662035). Cleaves the pectinesterases PME1 after the Arg-Arg-Leu-Met (RRLM) and Arg-Arg-Leu-Leu (RRLL) motifs, and PME5 after the Arg-Arg-Leu-Leu (RRLL) and Arg-Lys-Leu-Met (RKLM) motifs. This processing and C-terminus release occurs in the Golgi apparatus and is required for cell wall targeting of pectinesterases. Thus, SBT6.1 mediates the regulated release of mature pectinesterases from the Golgi (PubMed:19144003). Cleaves the peptide growth factor RALF23 after the Arg-Arg-Ile-Leu (RRIL) motif. This processing is required for RALF23 function in the negative regulation of brassinolide (BL)-mediated signaling pathway (e.g. BL-induced hypocotyl elongation and branching limitation) (PubMed:19473327). |
A0A1P8BD04_ARATH SBT61_ARATH | similarity | Belongs to the peptidase S8 family. |
SBT61_ARATH | tissue specificity | Expressed in the vasculature of roots, cotyledons and leaves. |
Function
Gene Ontology
cellular component | |
---|---|
Golgi apparatus | ECO |
Golgi membrane | ECO |
molecular function | |
endopeptidase activity | ECO |
serine-type endopeptidase activity | ECO |
biological process | |
proteolysis | ECO |
hyperosmotic response | ECO |
hyperosmotic salinity response | ECO |
Interactions
Interaction Network
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