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Gene : S1P A. thaliana

DB identifier  ? AT5G19660 Secondary Identifier  ? locus:2183224
Name  ? SITE-1 protease Brief Description  SITE-1 protease
TAIR Computational Description  SITE-1 protease;(source:Araport11)
TAIR Curator Summary  S1P appears to function as a Golgi-localized subtilase and to help protect seedlings against salt and osmotic stress. The roots of s1p-3 mutants are hypersensitive to NaCl, KCl, LiCl, and mannitol. Several salt-stress responsive genes show weaker induction in an s1P-3 mutant background. The proteolytic cleavage of the bZIP17 transcription factor depends on S1P in vitro. And there is evidence that S1P can cleave bZIP17 in vitro.The stability of ac4C-containing transcript encoded by At5g19660 was maintained by ac4C modification
TAIR Short Description  SITE-1 protease
TAIR Aliases  ATS1P, ATSBT6.1, S1P

2 Gene Rifs

1 Organism

13 Publications

0 Synonyms

Genomics

Genome feature

Region: gene ? Length: 4644  
Location: Chr5:6641907-6646550 reverse strand

Gene models - S1P AT5G19660

? Gene models

Transcripts: 3  Exons: 30  Introns: 27 

Overlapping Features

? Genome features that overlap coordinates of this Gene

17 Child Features

1 Cross References

1 Downstream Intergenic Region

0 Located Features

1 Upstream Intergenic Region

Proteins

Curated comments from UniProt

Type Comment Proteins
SBT61_ARATH function Serine protease that catalyzes the first step (site-1 cleavage) in the proteolytic activation of various factors, prior to site-2 cleavage. Part of a regulated intramembrane proteolysis (RIP) cascade. Cleaves BZIP17 and BZIP28 after the Arg-Arg-Ile-Leu (RRIL) motif. May cleave BZIP49 after the RRIL motif. Targets the membrane-associated BZIP17 factor, which functions as a stress sensor and transducer in a signaling pathway that resembles an ER stress response. Following salt stress, BZIP17 is cleaved by SBT6.1 (S1P) and S2P at the C-terminus and the N-terminal bZIP component is translocated to the nucleus, where it activates the expression of salt stress response genes (PubMed:17662035). Cleaves the pectinesterases PME1 after the Arg-Arg-Leu-Met (RRLM) and Arg-Arg-Leu-Leu (RRLL) motifs, and PME5 after the Arg-Arg-Leu-Leu (RRLL) and Arg-Lys-Leu-Met (RKLM) motifs. This processing and C-terminus release occurs in the Golgi apparatus and is required for cell wall targeting of pectinesterases. Thus, SBT6.1 mediates the regulated release of mature pectinesterases from the Golgi (PubMed:19144003). Cleaves the peptide growth factor RALF23 after the Arg-Arg-Ile-Leu (RRIL) motif. This processing is required for RALF23 function in the negative regulation of brassinolide (BL)-mediated signaling pathway (e.g. BL-induced hypocotyl elongation and branching limitation) (PubMed:19473327).
A0A1P8BD04_ARATH SBT61_ARATH similarity Belongs to the peptidase S8 family.
SBT61_ARATH tissue specificity Expressed in the vasculature of roots, cotyledons and leaves.

2 Proteins

Function

Gene Ontology

cellular component
Golgi apparatus  ? ECO  
Golgi membrane  ? ECO  
molecular function
endopeptidase activity  ? ECO  
serine-type endopeptidase activity  ? ECO  
biological process
proteolysis  ? ECO  
hyperosmotic response  ? ECO  
hyperosmotic salinity response  ? ECO  

Interactions

Interaction Network

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Expression

eFP Visualization

Data Source: BAR




Co-expression

Querying ATTED Service...
Data Source: ATTED-II
Top N
LS: LS is a monotonic transformation (negative logit) of MR index. Larger LS indicates stronger co-expression.

 

Homology

Phytozome Homologs

Data Source: Phytozome


0 Homologues

 

Other

8 Data Sets