Proteins
Curated comments from UniProt
Type | Comment | Proteins |
---|---|---|
ITPK1_ARATH | function | Kinase that can phosphorylate various inositol polyphosphate such as Ins(3,4,5,6)P4 or Ins(1,3,4)P3. Phosphorylates Ins(3,4,5,6)P4 at position 1 to form Ins(1,3,4,5,6)P5. This reaction is thought to have regulatory importance, since Ins(3,4,5,6)P4 is an inhibitor of plasma membrane Ca(2+)-activated Cl(-) channels, while Ins(1,3,4,5,6)P5 is not (By similarity). Also phosphorylates Ins(1,3,4)P3 on O-5 and O-6 to form Ins(1,3,4,6)P4, an essential molecule in the hexakisphosphate (InsP6) pathway (PubMed:9126335). |
ITPK1_ARATH | similarity | Belongs to the ITPK1 family. |
ITPK1_ARATH | tissue specificity | Expressed in siliques. |
Function
Gene Ontology
cellular component | |
---|---|
No terms in this category. | |
molecular function | |
ATP binding | ECO |
inositol-3,4,5,6-tetrakisphosphate 1-kinase activity | ECO |
inositol-1,3,4-trisphosphate 5-kinase activity | ECO |
inositol-1,3,4-trisphosphate 6-kinase activity | ECO |
magnesium ion binding | ECO |
biological process | |
inositol trisphosphate metabolic process | ECO |
myo-inositol hexakisphosphate biosynthetic process | ECO |
phosphorylation | ECO |
Interactions
Interaction Network
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