Proteins
Curated comments from UniProt
Type | Comment | Proteins |
---|---|---|
SUN1_ARATH | function | Component of SUN-protein-containing multivariate complexes also called LINC complexes which link the nucleoskeleton and cytoskeleton by providing versatile outer nuclear membrane attachment sites for cytoskeletal filaments (PubMed:24667841, PubMed:25759303). Required for the maintenance and/or formation of polarized nuclear shape in root hairs (PubMed:21294795, PubMed:25759303). Modulates the anchoring and mobility of WIP proteins and RANGAP1 in the nuclear envelope (NE) (PubMed:22270916). In association with SUN2, may be involved in telomere attachment to nuclear envelope in the prophase of meiosis (PubMed:25412930). As component of the SUN-WIP-WIT2-KAKU1 complex, mediates the transfer of cytoplasmic forces to the nuclear envelope (NE), leading to nuclear shape changes (PubMed:25759303). |
SUN1_ARATH | subcellular location | Dynamic localization during mitosis and meosis, tightly coupled with nuclear envelope (NE) dynamics. Localized with the nuclear envelope during meiotic prophase I. NE re-formation during metaphase is temporally and spatially coordinated with plant-specific microtubule structures such as phragmoplasts. During anaphase, after NE breakdown (NEBD), predominantly localized with the endoplasmic reticulum, in the outside of the segregated chromosomes and not in between segregated chromosomes. |
SUN1_ARATH | tissue specificity | Expressed in roots, hypocotyls, cotyledons and leaves and inflorescences. |
Function
Gene Ontology
cellular component | |
---|---|
endoplasmic reticulum | ECO |
endoplasmic reticulum membrane | ECO |
nuclear envelope | ECO |
cytoskeleton | ECO |
nuclear inner membrane | ECO |
phragmoplast | ECO |
molecular function | |
protein-membrane adaptor activity | ECO |
biological process | |
protein heterooligomerization | ECO |
protein homooligomerization | ECO |
protein localization to nuclear envelope | ECO |
regulation of establishment or maintenance of cell polarity regulating cell shape | ECO |
meiotic attachment of telomere to nuclear envelope | ECO |
nucleus organization | ECO |
Interactions
Interaction Network
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