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Gene : PAB2 A. thaliana

DB identifier  ? AT4G34110 Secondary Identifier  ? locus:2124261
Name  ? poly(A) binding protein 2 Brief Description  poly(A) binding protein 2
TAIR Computational Description  poly(A) binding protein 2;(source:Araport11)
TAIR Curator Summary  Putative poly-A binding protein. Member of a gene family .Expressed in stele and root meristem and post-fertilization ovules.Member of the class II family of PABP proteins. The mRNA is cell-to-cell mobile.
TAIR Short Description  poly(A) binding protein 2
TAIR Aliases  ATPAB2, PAB2, PABP2

3 Gene Rifs

1 Organism

29 Publications

0 Synonyms

Genomics

Genome feature

Region: gene ? Length: 4024  
Location: Chr4:16336291-16340314

Gene models - PAB2 AT4G34110

? Gene models

Transcripts: 1  Exons: 9  Introns: 8 

Overlapping Features

? Genome features that overlap coordinates of this Gene

10 Child Features

1 Cross References

1 Downstream Intergenic Region

0 Located Features

1 Upstream Intergenic Region

Proteins

Curated comments from UniProt

Type Comment Proteins
PABP2_ARATH function Binds the poly(A) tail of mRNA. Appears to be an important mediator of the multiple roles of the poly(A) tail in mRNA biogenesis, stability and translation. In the cytoplasm, affects both translation and mRNA decay. Stimulates translation by interaction with translation initiation factor eIF4G, a subunit of the cap-binding complex eIF4F, bringing the 5'- and 3'-ends of the mRNA in proximity. The formation of this circular mRNP structure appears to be critical for the synergistic effects of the cap and the poly(A) tail in facilitating translation initiation, recycling of ribosomes, and mRNA stability. During infection with potyvirus TuMV, acts as a potential integral component of the viral replicase complex that could play an important role in the regulation of potyviral RNA-dependent RNA polymerase (RdRp). Binds to uridylated mRNAs and determines the size of uridine extensions (PubMed:26972004). Limits uridine extension by URT1, likely by binding to the oligo(A) tail and preventing URT1 access (PubMed:26972004).
PABP2_ARATH similarity Belongs to the polyadenylate-binding protein type-1 family.
PABP2_ARATH subcellular location In TuMV-infected plants, partially retargeted in cytoplasmic virus-induced vesicles and in the nucleolus.
PABP2_ARATH tissue specificity Expressed in all organs (at the protein level) but under distinct spatial and temporal regulation within each organ.

1 Proteins

Function

Interactions

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Expression

eFP Visualization

Data Source: BAR




Co-expression

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Data Source: ATTED-II
Top N
LS: LS is a monotonic transformation (negative logit) of MR index. Larger LS indicates stronger co-expression.

 

Homology

Phytozome Homologs

Data Source: Phytozome


0 Homologues

 

Other

9 Data Sets