Genomics
Overlapping Features
Genome features that overlap coordinates of this Gene
CDSs: 4, Exons: 6, Five Prime UTR: 1, Gene: 1, mRNAs: 5, Three Prime UTRs: 3, Transposable Element: 1, Transposon Fragment: 1
Proteins
Curated comments from UniProt
Type | Comment | Proteins |
---|---|---|
P2C56_ARATH | function | Key component and repressor of the abscisic acid (ABA) signaling pathway that regulates numerous ABA responses, such as stomatal closure, osmotic water permeability of the plasma membrane (Pos), drought-induced resistance and rhizogenesis, response to glucose, high light stress, seed germination and inhibition of vegetative growth. During the stomatal closure regulation, modulates the inward calcium-channel permeability as well as the actin reorganization in guard cells in response to ABA. Involved in the resistance to the bacterial pathogen Pseudomonas syringae pv. tomato. Controls negatively fibrillin expression that is involved in mediating ABA-induced photoprotection. May be involved in ABA content regulation. Plays a role in the Pro accumulation in response to reduced water availability (low water potential). Required for the ABA negative regulation of the ethylene-induced hyponastic growth. Involved in acquired thermotolerance of root growth and seedling survival. Activates/represses SRK2E/OST1 in response to ABA-dependent stimuli, especially in stomata closure regulation involving SLAC1. Represses MAPKKK18 activity and promotes MAPKKK18 degradation by the proteasome pathway upon abscisic acid (ABA) treatment (PubMed:26443375). Represses KIN10 activity by the specific dephosphorylation of its T-loop Thr-198, leading to a poststress inactivation of SnRK1 signaling (PubMed:24179127). Restricts MAPKKK20 activity by dephosphorylation (PubMed:27913741). |
P2C56_ARATH | similarity | Belongs to the PP2C family. |
P2C56_ARATH | subcellular location | Associated to the plasma membrane when in complex with PA, subsequently to ABA signaling. |
P2C56_ARATH | tissue specificity | Expressed in seeds and seedlings. In roots, confined to lateral root caps and columella cells. |
Function
Gene Ontology
cellular component | |
---|---|
plasma membrane | ECO |
nucleus | ECO |
cytoplasm | ECO |
molecular function | |
phosphoprotein phosphatase activity | ECO |
protein kinase binding | ECO |
myosin phosphatase activity | ECO |
kinase binding | ECO |
phosphatase activity | ECO |
protein serine/threonine phosphatase activity | ECO |
metal ion binding | ECO |
biological process | |
response to heat | ECO |
regulation of abscisic acid-activated signaling pathway | ECO |
negative regulation of abscisic acid-activated signaling pathway | ECO |
abscisic acid-activated signaling pathway | ECO |
response to abscisic acid | ECO |
regulation of stomatal movement | ECO |
response to cold | ECO |
protein dephosphorylation | ECO |
Interactions
Interaction Network
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